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Product Details
H00010218-M07
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3A9
Immunogen
ANGPTL7 (NP_066969, 27 a.a. approximately 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD
Target Information
Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: angiopoietin-like 7; Angiopoietin-like factor; angiopoietin-like factor (CDT6); Angiopoietin-like protein 7; Angiopoietin-related protein 7; Cornea-derived transcript 6 protein
Gene Aliases: ANGPTL7; AngX; CDT6; dJ647M16.1; UNQ313/PRO356
UniProt ID: (Human) O43827
Entrez Gene ID: (Human) 10218
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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