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Invitrogen
ANGPTL7 Monoclonal Antibody (538401)
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FIGURE: 1 / 3
ANGPTL7 Antibody (MA5-24238) in IHC (F)
Immunohistochemical analysis of ANGPTL7 in perfusion fixed frozen sections of mouse brain. Samples were incubated in ANGPTL7 monoclonal antibody (Product # MA5-24238) using a dilution of 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in neurons.
Product Details
MA5-24238
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
538401
Immunogen
CHO-derived recombinant mouse Angiopoietin-like Protein 7/ANGPTL7 Gln22-Pro337 (predicted)
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606502
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Angiopoietin-like protein 7; Angiopoietin-related protein 7
Gene Aliases: Angptl7
UniProt ID: (Mouse) Q8R1Q3
Entrez Gene ID: (Mouse) 654812
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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