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Invitrogen
CD155 Monoclonal Antibody (3F1)
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Product Details
MA5-33379
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
3F1
Immunogen
Ectodomain of recombinant His-tagged CD155
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
Protein G
Storage buffer
PBS with 0.1% BSA
Contains
no preservative
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2815517
Product Specific Information
Product is supplied at 1 mL (100 µL/mL).
Application Notes: Flow cytometry - This antibody stains the extracellular domain of mouse CD155. The thymocytes were blocked with 5% mouse serum before incubation with clone 3F1 for 1 hour at 4°C As positive control CD4+CD8+ thymocytes was used and as negative control CD155-/- derived cells. Functional Assay- This antibody functions as antagonist. The antibody was functionally tested by blocking adhesion of Sf9 cells expressing mCD155 to RMA, CD4+ and CD8+ cells. Furthermore, antibody clone 3F1 prevents formation of mCD155/ligand complexes. Positive control: CD4+CD8+ mouse thymocytes; Negative control: CD155-/- cells.
Target Information
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ25946; nectin-like 5; poliovirus receptor; sCD112; soluble CD112; tumor-associated antigen 1
Gene Aliases: 3830421F03Rik; CD155; D7Ertd458e; HVED; mE4; necl-5; PVS; Taa1; Tage4
Entrez Gene ID: (Mouse) 52118
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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