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Invitrogen
Human IgG3 Recombinant Rabbit Monoclonal Antibody (6Q4J8)
FIGURE: 1 / 1
Human IgG3 Antibody (MA5-42730) in WB
Western blot analysis of Human IgG3 in extracts of Human plasma. Samples were incubated with Human IgG3 Monoclonal antibody (Product # MA5-42730) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
MA5-42730
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6Q4J8
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IgG3 (P01860)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911871
Product Specific Information
Positive test controls include: human plasma.
Immunogen sequence: VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ TYTCNVNHKP SNTKVDKRVE LKTPLGDTTH TCPRCPEPKS CDTPPPCPRC PEPKSCDTPP PCPRCPEPKS C
Target Information
Human IgG3, also known as human immunoglobulin G3, is a subclass of human IgG antibodies that is produced by the immune system in response to antigens. It is the least abundant subclass of IgG in the blood and plays a minor role in defense against pathogens. IgG3 works by binding to specific antigens and promoting their clearance from the body through various mechanisms, including phagocytosis and complement activation. IgG3 is also involved in other immune responses, such as antibody-dependent cellular cytotoxicity and neutralization of toxins. Human IgG3 can be used in research to study the immune response to pathogens and to develop diagnostic tests and therapeutic interventions for infectious and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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