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Product Details
H00007064-M01A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM, kappa
Class
Monoclonal
Type
Antibody
Clone
2B4
Immunogen
THOP1 (NP_003240.1, 255 a.a. approximately 354 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: ILKELVTLRA QKSRLLGFHT HADYVLEMNM AKTSQTVATF LDELAQKLKP LGEQERAVIL ELKRAECERR GLPFDGRIRA WDMRYYMNQV EETRYCVDQN
Target Information
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.4.24; EC 3.4.24.15; Endopeptidase 24.15; MP78; Thimet oligopeptidase
Gene Aliases: EP24.15; MEPD_HUMAN; MP78; THOP1; TOP
UniProt ID: (Human) P52888
Entrez Gene ID: (Human) 7064
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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