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Bioss
THOP1/Thimet Oligopeptidase Polyclonal Antibody
Product Details
BS-11683R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Thimet Oligopeptidase, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.4.24; EC 3.4.24.15; Endo-oligopeptidase A; Endopeptidase 24.15; metalloendopeptidase; MP78; PZ-peptidase; Soluble metallo-endopeptidase; Thimet oligopeptidase
Gene Aliases: AI131655; AI327041; EP24.15; MEPD_HUMAN; MP78; THOP1; TOP
UniProt ID: (Human) P52888, (Mouse) Q8C1A5, (Rat) P24155
Entrez Gene ID: (Human) 7064, (Mouse) 50492, (Rat) 64517
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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