Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Human Cluster of Differentiation 6/CD6 quantitates human Cluster of Differentiation 6/CD6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cluster of Differentiation 6/CD6.
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CD6, TP120
Gene ID : (Human) 923
Gene symbol : CD6
Protein Aliases : CD6, CD6 antigen, FLJ44171, T-cell differentiation antigen CD6, T12, TP120
UniProt ID (Human) P30203
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