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Human SHBG quantitates human SHBG in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SHBG.
SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ABP, SBP, SHBG, TEBG
Gene ID : (Human) 6462
Gene symbol : SHBG
Protein Aliases : ABP, SBP, Sex hormone-binding globulin, Sex steroid-binding protein, SHBG, TeBG, Testis-specific androgen-binding protein, Testosterone binding beta globulin, Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Testosterone-Estradiol-Binding Globulin (TEBG), Androgen binding protein (ABP), testosterone-binding beta-globulin, Testosterone-estradiol-binding globulin, Testosterone-estrogen-binding globulin
UniProt ID (Human) P04278
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