Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Human SMPD1 quantitates human SMPD1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SMPD1.
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ASM, ASMASE, NPD, SMPD1
Gene ID : (Human) 6609
Gene symbol : SMPD1
Protein Aliases : Acid sphingomyelinase, aSMase, Sphingomyelin phosphodiesterase, sphingomyelin phosphodiesterase 1, acid lysosomal
UniProt ID (Human) P17405
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