Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Porcine TGF alpha quantitates porcine TGF alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant porcine TGF alpha.
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : TGFA
Gene ID : (Pig) 397484
Gene symbol : TGFA
Protein Aliases : Protransforming growth factor alpha, TGF a, TGF α, TGFalpha, TGFα, Transforming growth factor, transforming growth factor alpha
UniProt ID (Pig) Q06922
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