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Product Specifications
Analytical sensitivity
Lot-specific
Assay range
Lot-specific
Hands-on time
1 hr 45 min
Time-to-result
24 hr 30 min
Homogenous (no wash)
No
Instrument
Absorbance Microplate Reader
Product size
10 x 96 Tests
Contents
This Rat CCL3 (MIP-1 alpha) ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately.
Storage
Refer to product documentation for component specific storage temperature.
Protein name
CCL3 (MIP-1 alpha)
Protein family
Growth Factors & Receptors
Species (tested)
Rat
Assay kit format
ELISA Development Kit
Detector antibody conjugate
Biotin
Label or dye
HRP
About This Kit
900-K75K consists of: 900-K75 (capture antibody, detection antibody, and protein standard), and AVIDIN-60UL (avidin HRP-conjugate).
Rat CCL3 (MIP-1 alpha) ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant rat CCL3 (MIP-1 alpha) in a sandwich ELISA format. Rat CCL3 (MIP-1 alpha) ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
Target information
Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : Ccl3, MIP-1a, Mip1a, Scya3
Gene ID : (Rat) 25542
Gene symbol : Ccl3
Protein Aliases : C-C motif chemokine 3, Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3), Macrophage inflammatory protein 1-alpha, MIP-1-alpha, mip1 alpha, H-MIP-1-alpha, LD78-alpha, RP23-320E6.7, small inducible cytokine A3, Small-inducible cytokine A3
UniProt ID (Rat) P50229
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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