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Invitrogen
Human Angiostatin Native Protein
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Product Details
RP-43140
Product Specifications
Species
Human
Molecular weight
50 kDa
Class
Native
Type
Protein
Conjugate
Form
Liquid
Concentration
4.7 mg/mL
Purification
SDS-PAGE
Storage buffer
0.02M HEPES, pH 7.4, with 0.15M NaCl
Contains
no preservative
Storage conditions
-80°C
Shipping conditions
Dry ice
Product Specific Information
RP-43140 contains native human Angiostatin protein.
RP-43140 may be used as a positive control in many immunological assays.
The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.
This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!
Target Information
The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Microplasmin; plasmin; Plasminogen
Gene Aliases: PLG
UniProt ID: (Human) P00747
Entrez Gene ID: (Human) 5340
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