Product References
CC chemokine receptor 7 promotes macrophage recruitment and induces M2-polarization through CC chemokine ligand 19&21 in oral squamous cell carcinoma.
Discover oncology
Zhou WH,Wang Y,Yan C,Du WD,Al-Aroomi MA,Zheng L,Lin SF,Gao JX,Jiang S,Wang ZX,Sun CF,Liu FY
300-29B was used in In vitro experiments to investigate CCR7 in tumour associated macrophage recruitment of oral squamous cell carcinoma.
Fri Jul 29 00:00:00 UTC 2022
CAL-1 as Cellular Model System to Study CCR7-Guided Human Dendritic Cell Migration.
Frontiers in immunology
Uetz-von Allmen E,Samson GPB,Purvanov V,Maeda T,Legler DF
300-29B was used in In vitro experiments to show that the previously established human neoplastic cell line CAL-1 expresses the human dendritic cell surface antigens CD11c and HLA-DR together with co-stimulatory molecules.
Mon Dec 13 00:00:00 UTC 2021
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Nature communications
Gurusamy M,Tischner D,Shao J,Klatt S,Zukunft S,Bonnavion R,Günther S,Siebenbrodt K,Kestner RI,Kuhlmann T,Fleming I,Offermanns S,Wettschureck N
Tue Nov 23 00:00:00 UTC 2021
A tissue-like platform for studying engineered quiescent human T-cells' interactions with dendritic cells.
eLife
Abu-Shah E,Demetriou P,Bálint Š,Mayya V,Kutuzov MA,Dushek O,Dustin ML
300-29B was used in Sample Preparation to report a tissue-like system that recapitulates the dynamics of engineered primary human immune cell and characterise unique dynamics of T-cell/DC interactions as a function of antigen affinity.
Wed Sep 25 00:00:00 UTC 2019
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
The Journal of biological chemistry
Lee AW,Deruaz M,Lynch C,Davies G,Singh K,Alenazi Y,Eaton JRO,Kawamura A,Shaw J,Proudfoot AEI,Dias JM,Bhattacharya S
Fri Jul 19 00:00:00 UTC 2019
Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides.
Cell death & disease
Zhang G,Luk BT,Wei X,Campbell GR,Fang RH,Zhang L,Spector SA
Wed May 29 00:00:00 UTC 2019
SMAC Mimetics Induce Autophagy-Dependent Apoptosis of HIV-1-Infected Resting Memory CD4+ T Cells.
Cell host & microbe
Campbell GR,Bruckman RS,Chu YL,Trout RN,Spector SA
300-29B was used in Cell Culture to study how DIABLO/SMAC mimetics (birinapant, GDC-0152, and embelin) selectively kill HIV-Long-lived resting memory CD4+ T cells (TCM) without increasing virus production or targeting uninfected TCM.
Wed Nov 14 00:00:00 UTC 2018
Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.
Proceedings of the National Academy of Sciences of the United States of America
Lahvic JL,Ammerman M,Li P,Blair MC,Stillman ER,Fast EM,Robertson AL,Christodoulou C,Perlin JR,Yang S,Chiang N,Norris PC,Daily ML,Redfield SE,Chan IT,Chatrizeh M,Chase ME,Weis O,Zhou Y,Serhan CN,Zon LI
Tue Sep 11 00:00:00 UTC 2018
Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.
Proceedings of the National Academy of Sciences of the United States of America
Lahvic JL,Ammerman M,Li P,Blair MC,Stillman ER,Fast EM,Robertson AL,Christodoulou C,Perlin JR,Yang S,Chiang N,Norris PC,Daily ML,Redfield SE,Chan IT,Chatrizeh M,Chase ME,Weis O,Zhou Y,Serhan CN,Zon LI
Tue Sep 11 00:00:00 UTC 2018
Lymphatic exosomes promote dendritic cell migration along guidance cues.
The Journal of cell biology
Brown M,Johnson LA,Leone DA,Majek P,Vaahtomeri K,Senfter D,Bukosza N,Schachner H,Asfour G,Langer B,Hauschild R,Parapatics K,Hong YK,Bennett KL,Kain R,Detmar M,Sixt M,Jackson DG,Kerjaschki D
Mon Jun 04 00:00:00 UTC 2018
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
Scientific reports
Alenazi Y,Singh K,Davies G,Eaton JRO,Elders P,Kawamura A,Bhattacharya S
Fri Apr 20 00:00:00 UTC 2018
Identification of Cosalane as an Inhibitor of Human and Murine CC-Chemokine Receptor 7 Signaling via a High-Throughput Screen.
SLAS discovery : advancing life sciences R & D
Hull-Ryde EA,Porter MA,Fowler KA,Kireev D,Li K,Simpson CD,Sassano MF,Suto MJ,Pearce KH,Janzen W,Coghill JM
300-29B was used in In vitro experiments to unravel and validate cosalane as a CCR7 antagosnist, that inhibits the respective chemokine receptors in rodents and humans both.
Sat Dec 01 00:00:00 UTC 2018
Identification of Cosalane as an Inhibitor of Human and Murine CC-Chemokine Receptor 7 Signaling via a High-Throughput Screen.
SLAS discovery : advancing life sciences R & D
Hull-Ryde EA,Porter MA,Fowler KA,Kireev D,Li K,Simpson CD,Sassano MF,Suto MJ,Pearce KH,Janzen W,Coghill JM
300-29B was used in In vitro experiments to unravel and validate cosalane as a CCR7 antagosnist, that inhibits the respective chemokine receptors in rodents and humans both.
Sat Dec 01 00:00:00 UTC 2018
Compromised functionality of monocyte-derived dendritic cells in multiple myeloma patients may limit their use in cancer immunotherapy.
Scientific reports
Shinde P,Fernandes S,Melinkeri S,Kale V,Limaye L
Mon Apr 09 00:00:00 UTC 2018
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.
Immunity
Kishore M,Cheung KCP,Fu H,Bonacina F,Wang G,Coe D,Ward EJ,Colamatteo A,Jangani M,Baragetti A,Matarese G,Smith DM,Haas R,Mauro C,Wraith DC,Okkenhaug K,Catapano AL,De Rosa V,Norata GD,Marelli-Berg FM
300-29B was used in Sample Preparation to demonstrate that glucokinase-dependent glycolysis regulates regulatory T cell migration.
Tue Nov 21 00:00:00 UTC 2017
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.
Immunity
Kishore M,Cheung KCP,Fu H,Bonacina F,Wang G,Coe D,Ward EJ,Colamatteo A,Jangani M,Baragetti A,Matarese G,Smith DM,Haas R,Mauro C,Wraith DC,Okkenhaug K,Catapano AL,De Rosa V,Norata GD,Marelli-Berg FM
300-29B was used in Sample Preparation to demonstrate that glucokinase-dependent glycolysis regulates regulatory T cell migration.
Tue Nov 21 00:00:00 UTC 2017
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Scientific reports
Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S
Tue Jun 27 00:00:00 UTC 2017
Functional Langerinhigh-Expressing Langerhans-like Cells Can Arise from CD14highCD16- Human Blood Monocytes in Serum-Free Condition.
Journal of immunology (Baltimore, Md. : 1950)
Picarda G,Chéneau C,Humbert JM,Bériou G,Pilet P,Martin J,Duteille F,Perrot P,Bellier-Waast F,Heslan M,Haspot F,Guillon F,Josien R,Halary FA
Sun May 01 00:00:00 UTC 2016
The Mammalian Sterile 20-like 1 Kinase Controls Selective CCR7-Dependent Functions in Human Dendritic Cells.
Journal of immunology (Baltimore, Md. : 1950)
Torres-Bacete J,Delgado-Martín C,Gómez-Moreira C,Simizu S,Rodríguez-Fernández JL
Sat Aug 01 00:00:00 UTC 2015
Galectin-1 regulates tissue exit of specific dendritic cell populations.
The Journal of biological chemistry
Thiemann S,Man JH,Chang MH,Lee B,Baum LG
Fri Sep 11 00:00:00 UTC 2015
Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide.
Blood
Ramsay AG,Evans R,Kiaii S,Svensson L,Hogg N,Gribben JG
Thu Apr 04 00:00:00 UTC 2013
KIR2DS1-dependent acquisition of CCR7 and migratory properties by human NK cells interacting with allogeneic HLA-C2+ DCs or T-cell blasts.
Blood
Marcenaro E,Pesce S,Sivori S,Carlomagno S,Moretta L,Moretta A
Thu Apr 25 00:00:00 UTC 2013
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR.
The Journal of biological chemistry
Watts AO,Verkaar F,van der Lee MM,Timmerman CA,Kuijer M,van Offenbeek J,van Lith LH,Smit MJ,Leurs R,Zaman GJ,Vischer HF
Fri Mar 08 00:00:00 UTC 2013
Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function.
Blood
Dannull J,Schneider T,Lee WT,de Rosa N,Tyler DS,Pruitt SK
Thu Mar 29 00:00:00 UTC 2012
L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Freeley M,O'Dowd F,Paul T,Kashanin D,Davies A,Kelleher D,Long A
Fri Jun 15 00:00:00 UTC 2012
Adenosine deaminase enhances the immunogenicity of human dendritic cells from healthy and HIV-infected individuals.
PloS one
Casanova V,Naval-Macabuhay I,Massanella M,Rodríguez-García M,Blanco J,Gatell JM,García F,Gallart T,Lluis C,Mallol J,Franco R,Climent N,McCormick PJ
Thu May 30 00:00:00 UTC 2013
CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration.
Blood
Quast T,Eppler F,Semmling V,Schild C,Homsi Y,Levy S,Lang T,Kurts C,Kolanus W
Thu Aug 18 00:00:00 UTC 2011
Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression.
Proceedings of the National Academy of Sciences of the United States of America
Guenin-Macé L,Carrette F,Asperti-Boursin F,Le Bon A,Caleechurn L,Di Bartolo V,Fontanet A,Bismuth G,Demangel C
Tue Aug 02 00:00:00 UTC 2011
Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration.
Journal of immunology (Baltimore, Md. : 1950)
Schaeuble K,Hauser MA,Singer E,Groettrup M,Legler DF
Thu Dec 01 00:00:00 UTC 2011
Chemokine CXCL12 uses CXCR4 and a signaling core formed by bifunctional Akt, extracellular signal-regulated kinase (ERK)1/2, and mammalian target of rapamycin complex 1 (mTORC1) proteins to control chemotaxis and survival simultaneously in mature dendritic cells.
The Journal of biological chemistry
Delgado-Martín C,Escribano C,Pablos JL,Riol-Blanco L,Rodríguez-Fernández JL
Fri Oct 28 00:00:00 UTC 2011
Dendritic cells exposed to MVA-based HIV-1 vaccine induce highly functional HIV-1-specific CD8(+) T cell responses in HIV-1-infected individuals.
PloS one
Climent N,Guerra S,García F,Rovira C,Miralles L,Gómez CE,Piqué N,Gil C,Gatell JM,Esteban M,Gallart T
Mon Nov 28 00:00:00 UTC 2011
Host chemokines bind to Staphylococcus aureus and stimulate protein A release.
The Journal of biological chemistry
Yung SC,Parenti D,Murphy PM
Fri Feb 18 00:00:00 UTC 2011
Uncarinic Acid C Isolated from Uncaria rhynchophylla Induces Differentiation of Th1-Promoting Dendritic Cells Through TLR4 Signaling.
Biomarker insights
Kim KS,Pham TN,Jin CJ,Umeyama A,Shoji N,Hashimoto T,Lee JJ,Takei M
Mon Feb 28 00:00:00 UTC 2011
PGE(2) transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive T cells.
Blood
Muthuswamy R,Mueller-Berghaus J,Haberkorn U,Reinhart TA,Schadendorf D,Kalinski P
Thu Sep 02 00:00:00 UTC 2010
Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Pareek TK,Lam E,Zheng X,Askew D,Kulkarni AB,Chance MR,Huang AY,Cooke KR,Letterio JJ
Mon Oct 25 00:00:00 UTC 2010
Chemokine scavenger D6 is expressed by trophoblasts and aids the survival of mouse embryos transferred into allogeneic recipients.
Journal of immunology (Baltimore, Md. : 1950)
Madigan J,Freeman DJ,Menzies F,Forrow S,Nelson SM,Young A,Sharkey A,Moffett A,Graham GJ,Greer IA,Rot A,Nibbs RJ
Mon Mar 15 00:00:00 UTC 2010
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Nature
Buonamici S,Trimarchi T,Ruocco MG,Reavie L,Cathelin S,Mar BG,Klinakis A,Lukyanov Y,Tseng JC,Sen F,Gehrie E,Li M,Newcomb E,Zavadil J,Meruelo D,Lipp M,Ibrahim S,Efstratiadis A,Zagzag D,Bromberg JS,Dustin ML,Aifantis I
Thu Jun 18 00:00:00 UTC 2009
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Nature
Buonamici S,Trimarchi T,Ruocco MG,Reavie L,Cathelin S,Mar BG,Klinakis A,Lukyanov Y,Tseng JC,Sen F,Gehrie E,Li M,Newcomb E,Zavadil J,Meruelo D,Lipp M,Ibrahim S,Efstratiadis A,Zagzag D,Bromberg JS,Dustin ML,Aifantis I
Thu Jun 18 00:00:00 UTC 2009
An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression.
Blood
Trinidad EM,Ballesteros M,Zuloaga J,Zapata A,Alonso-Colmenar LM
Thu Dec 03 00:00:00 UTC 2009
CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.
Blood
Gollmer K,Asperti-Boursin F,Tanaka Y,Okkenhaug K,Vanhaesebroeck B,Peterson JR,Fukui Y,Donnadieu E,Stein JV
Thu Jul 16 00:00:00 UTC 2009
Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis.
Arthritis research & therapy
Nanki T,Takada K,Komano Y,Morio T,Kanegane H,Nakajima A,Lipsky PE,Miyasaka N
Wed Feb 03 00:00:00 UTC 2010
Cysteinyl-leukotriene receptor type 1 expression and function is down-regulated during monocyte-derived dendritic cell maturation with zymosan: involvement of IL-10 and prostaglandins.
Journal of immunology (Baltimore, Md. : 1950)
Thivierge M,Stankova J,Rola-Pleszczynski M
Sun Nov 15 00:00:00 UTC 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 UTC 2009
Human cytomegalovirus paralyzes macrophage motility through down-regulation of chemokine receptors, reorganization of the cytoskeleton, and release of macrophage migration inhibitory factor.
Journal of immunology (Baltimore, Md. : 1950)
Frascaroli G,Varani S,Blankenhorn N,Pretsch R,Bacher M,Leng L,Bucala R,Landini MP,Mertens T
Thu Jan 01 00:00:00 UTC 2009
Anthrax edema toxin induces maturation of dendritic cells and enhances chemotaxis towards macrophage inflammatory protein 3beta.
Infection and immunity
Maldonado-Arocho FJ,Bradley KA
Fri May 01 00:00:00 UTC 2009
Bone marrow-derived dendritic cells generated in the presence of resolvin E1 induce apoptosis of activated CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Vassiliou EK,Kesler OM,Tadros JH,Ganea D
Wed Oct 01 00:00:00 UTC 2008
Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Lim HW,Lee J,Hillsamer P,Kim CH
Tue Jan 01 00:00:00 UTC 2008
Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors.
Stem cells (Dayton, Ohio)
Honczarenko M,Le Y,Swierkowski M,Ghiran I,Glodek AM,Silberstein LE
Sat Apr 01 00:00:00 UTC 2006
CC-chemokine ligand 16 induces a novel maturation program in human immature monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Cappello P,Fraone T,Barberis L,Costa C,Hirsch E,Elia AR,Caorsi C,Musso T,Novelli F,Giovarelli M
Wed Nov 01 00:00:00 UTC 2006
Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Lim HW,Broxmeyer HE,Kim CH
Sat Jul 15 00:00:00 UTC 2006
Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin.
The Journal of experimental medicine
Vermi W,Riboldi E,Wittamer V,Gentili F,Luini W,Marrelli S,Vecchi A,Franssen JD,Communi D,Massardi L,Sironi M,Mantovani A,Parmentier M,Facchetti F,Sozzani S
Mon Feb 21 00:00:00 UTC 2005
Human herpesvirus 7 open reading frames U12 and U51 encode functional beta-chemokine receptors.
Journal of virology
Tadagaki K,Nakano K,Yamanishi K
Wed Jun 01 00:00:00 UTC 2005
Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo.
Blood
Biragyn A,Ruffini PA,Coscia M,Harvey LK,Neelapu SS,Baskar S,Wang JM,Kwak LW
Fri Oct 01 00:00:00 UTC 2004
CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor.
Blood
Honczarenko M,Le Y,Glodek AM,Majka M,Campbell JJ,Ratajczak MZ,Silberstein LE
Tue Oct 01 00:00:00 UTC 2002
CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines.
The Journal of biological chemistry
Schweickart VL,Epp A,Raport CJ,Gray PW
Fri Mar 31 00:00:00 UTC 2000
