Product References
The Combination Treatment of Curcumin and Probucol Protects Chondrocytes from TNF-α Induced Inflammation by Enhancing Autophagy and Reducing Apoptosis via the PI3K-Akt-mTOR Pathway.
Oxidative medicine and cellular longevity
Han G,Zhang Y,Li H
Wed Jan 05 00:00:00 UTC 2022
Comparative bioinformatics analysis between proteomes of rabbit aneurysm model and human intracranial aneurysm with label-free quantitative proteomics.
CNS neuroscience & therapeutics
Liu Y,Song Y,Liu P,Li S,Shi Y,Yu G,Quan K,Fan Z,Li P,An Q,Zhu W
Fri Jan 01 00:00:00 UTC 2021
Protective effect of baicalin against pulmonary arterial hypertension vascular remodeling through regulation of TNF-α signaling pathway.
Pharmacology research & perspectives
Xue X,Zhang S,Jiang W,Wang J,Xin Q,Sun C,Li K,Qi T,Luan Y
Mon Feb 01 00:00:00 UTC 2021
Mesenchymal stem cells alleviate rat diabetic nephropathy by suppressing CD103+ DCs-mediated CD8+ T cell responses.
Journal of cellular and molecular medicine
Zhang F,Wang C,Wen X,Chen Y,Mao R,Cui D,Li L,Liu J,Chen Y,Cheng J,Lu Y
Fri May 01 00:00:00 UTC 2020
TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity.
Cell death & disease
Brás JP,Bravo J,Freitas J,Barbosa MA,Santos SG,Summavielle T,Almeida MI
Tue Jun 02 00:00:00 UTC 2020
Location and Plasticity of the Sodium Spike Initiation Zone in Nociceptive Terminals In Vivo.
Neuron
Goldstein RH,Barkai O,Íñigo-Portugués A,Katz B,Lev S,Binshtok AM
Wed May 22 00:00:00 UTC 2019
Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization.
Cells
Astakhova A,Chistyakov D,Thomas D,Geisslinger G,Brüne B,Sergeeva M,Namgaladze D
400-14 was used in In vitro experiments to indicate modulation of astrocyte inflammatory responses by oxidative metabolism, with relevance towards eicosanoid production.
Tue Oct 01 00:00:00 UTC 2019
Mesenchymal stem cells overexpressing heme oxygenase-1 ameliorate lipopolysaccharide-induced acute lung injury in rats.
Journal of cellular physiology
Chen X,Wu S,Tang L,Ma L,Wang F,Feng H,Meng J,Han Z
400-14 was used in In vitro experiments to provide a novel insight into MSC-based therapeutic strategies for treating ALI/ARDS.
Wed May 01 00:00:00 UTC 2019
Upregulation of caveolin-1 and its colocalization with cytokine receptors contributes to beta cell apoptosis.
Scientific reports
Bae GD,Park EY,Kim K,Jang SE,Jun HS,Oh YS
Thu Nov 14 00:00:00 UTC 2019
Effects of IL-10- and FasL-overexpressing dendritic cells on liver transplantation tolerance in a heterotopic liver transplantation rat model.
Immunology and cell biology
Chen L,Zhang L,Zhu Z,He W,Gao L,Zhang W,Liu J,Huang A
400-14 was used in Cell Culture to demonstrate that the transfusion of IL-10-FasL/imDCs enhanced immune tolerance and prolonged the survival of liver allografts after LT.
Sun Sep 01 00:00:00 UTC 2019
Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats.
Journal of cellular and molecular medicine
Wang J,Huang C,Lin Z,Pan X,Chen J,Zheng G,Tian N,Yan Y,Zhang Z,Hu J,Cheng P,Wang X,Zhang X
Thu Nov 01 00:00:00 UTC 2018
The distinct roles of mesenchymal stem cells in the initial and progressive stage of hepatocarcinoma.
Cell death & disease
Zong C,Zhang H,Yang X,Gao L,Hou J,Ye F,Jiang J,Yang Y,Li R,Han Z,Wei L
Thu Mar 01 00:00:00 UTC 2018
Omentectomy Prevents Metabolic Syndrome By Reducing Appetite and Body Weight In A Diet-Induced Obesity Rat Model.
Scientific reports
García-Ruiz I,Solís-Muñoz P,Fernández-Moreira D,Grau M,Muñoz-Yagüe MT,Solís-Herruzo JA
Wed Jan 24 00:00:00 UTC 2018
Deletion of F4L (ribonucleotide reductase) in vaccinia virus produces a selective oncolytic virus and promotes anti-tumor immunity with superior safety in bladder cancer models.
EMBO molecular medicine
Potts KG,Irwin CR,Favis NA,Pink DB,Vincent KM,Lewis JD,Moore RB,Hitt MM,Evans DH
Mon May 01 00:00:00 UTC 2017
Bone regeneration is associated with the concentration of tumour necrosis factor-α induced by sericin released from a silk mat.
Scientific reports
Jo YY,Kweon H,Kim DW,Baek K,Kim MK,Kim SG,Chae WS,Choi JY,Rotaru H
Tue Nov 14 00:00:00 UTC 2017
Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication.
The Journal of biological chemistry
Schneider DJ,Speth JM,Penke LR,Wettlaufer SH,Swanson JA,Peters-Golden M
Fri Dec 22 00:00:00 UTC 2017
Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration.
Nature communications
Gordon R,Neal ML,Luo J,Langley MR,Harischandra DS,Panicker N,Charli A,Jin H,Anantharam V,Woodruff TM,Zhou QY,Kanthasamy AG,Kanthasamy A
Wed Oct 05 00:00:00 UTC 2016
Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
The Journal of biological chemistry
Li J,Yuan W,Jiang S,Ye W,Yang H,Shapiro IM,Risbud MV
Fri Mar 13 00:00:00 UTC 2015
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) signaling and cell death in the immature central nervous system after hypoxia-ischemia and inflammation.
The Journal of biological chemistry
Kichev A,Rousset CI,Baburamani AA,Levison SW,Wood TL,Gressens P,Thornton C,Hagberg H
Fri Mar 28 00:00:00 UTC 2014
Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-α and IL-1β-induced Na-K-Cl Cotransporter up-regulation.
Journal of neuroinflammation
Huang LQ,Zhu GF,Deng YY,Jiang WQ,Fang M,Chen CB,Cao W,Wen MY,Han YL,Zeng HK
400-14 was used in Cell Culture to explore if alleviation of cerebral edema by 10% HS might be effected through down-regulation of inflammatory mediator expression in the microglia, and thus result in decreased NKCC1 expression in astrocytes in the cerebral cortex bordering the ischemic core.
Wed Jun 11 00:00:00 UTC 2014
Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α.
PloS one
Shao M,Yue Y,Sun GY,You QH,Wang N,Zhang D
Mon Jul 22 00:00:00 UTC 2013
Ferroportin-1 is a 'nuclear'-negative acute-phase protein in rat liver: a comparison with other iron-transport proteins.
Laboratory investigation; a journal of technical methods and pathology
Naz N,Malik IA,Sheikh N,Ahmad S,Khan S,Blaschke M,Schultze F,Ramadori G
Fri Jun 01 00:00:00 UTC 2012
COUP-TFII controls mouse pancreatic β-cell mass through GLP-1-β-catenin signaling pathways.
PloS one
Boutant M,Ramos OH,Tourrel-Cuzin C,Movassat J,Ilias A,Vallois D,Planchais J,Pégorier JP,Schuit F,Petit PX,Bossard P,Maedler K,Grapin-Botton A,Vasseur-Cognet M
Mon Jun 04 00:00:00 UTC 2012
Gene network revealed involvements of Birc2, Birc3 and Tnfrsf1a in anti-apoptosis of injured peripheral nerves.
PloS one
Wang Y,Tang X,Yu B,Gu Y,Yuan Y,Yao D,Ding F,Gu X
Tue Mar 19 00:00:00 UTC 2013
Rat mesenchymal stromal cells inhibit T cell proliferation but not cytokine production through inducible nitric oxide synthase.
Frontiers in immunology
Zinöcker S,Vaage JT
Thu Aug 23 00:00:00 UTC 2012
Intraperitoneal but not intravenous cryopreserved mesenchymal stromal cells home to the inflamed colon and ameliorate experimental colitis.
PloS one
Castelo-Branco MT,Soares ID,Lopes DV,Buongusto F,Martinusso CA,do Rosario A,Souza SA,Gutfilen B,Fonseca LM,Elia C,Madi K,Schanaider A,Rossi MI,Souza HS
Fri Jul 13 00:00:00 UTC 2012
Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells.
Journal of neuroinflammation
Tanabe K,Matsushima-Nishiwaki R,Yamaguchi S,Iida H,Dohi S,Kozawa O
Sat Mar 06 00:00:00 UTC 2010
Glyconanoparticles allow pre-symptomatic in vivo imaging of brain disease.
Proceedings of the National Academy of Sciences of the United States of America
van Kasteren SI,Campbell SJ,Serres S,Anthony DC,Sibson NR,Davis BG
Tue Jan 06 00:00:00 UTC 2009
Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease.
The Journal of investigative dermatology
Sadri N,Schneider RJ
Sun Mar 01 00:00:00 UTC 2009
Tumor necrosis factor-alpha modulates glutamate transport in the CNS and is a critical determinant of outcome from viral encephalomyelitis.
Brain research
Carmen J,Rothstein JD,Kerr DA
400-14 was used in Tissue/organ culture to show that these findings have implications for disease intervention and therapeutic development for the prevention of CNS damage associated with inflammatory responses.
Tue Mar 31 00:00:00 UTC 2009
Microglial activation and TNFalpha production mediate altered CNS excitability following peripheral inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Riazi K,Galic MA,Kuzmiski JB,Ho W,Sharkey KA,Pittman QJ
Tue Nov 04 00:00:00 UTC 2008
Effect of inflammatory cytokines on major histocompatibility complex expression and differentiation of human neural stem/progenitor cells.
Stem cells (Dayton, Ohio)
Johansson S,Price J,Modo M
Mon Sep 01 00:00:00 UTC 2008
Age-related differences in NFkappaB translocation and Bcl-2/Bax ratio caused by TNFalpha and Abeta42 promote survival in middle-age neurons and death in old neurons.
Experimental neurology
Patel JR,Brewer GJ
Mon Sep 01 00:00:00 UTC 2008
Expression and regulation of major histocompatibility complex on neural stem cells and their lineages.
Stem cells and development
Yin L,Fu SL,Shi GY,Li Y,Jin JQ,Ma ZW,Lu PH
Fri Feb 01 00:00:00 UTC 2008
Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis.
Journal of neuroinflammation
Mueller AM,Pedré X,Stempfl T,Kleiter I,Couillard-Despres S,Aigner L,Giegerich G,Steinbrecher A
Mon May 26 00:00:00 UTC 2008
x-Irradiation in rat liver: consequent upregulation of hepcidin and downregulation of hemojuvelin and ferroportin-1 gene expression.
Radiology
Christiansen H,Sheikh N,Saile B,Reuter F,Rave-Fränk M,Hermann RM,Dudas J,Hille A,Hess CF,Ramadori G
Mon Jan 01 00:00:00 UTC 2007
Adenosine and TNF-alpha exert similar inotropic effect on heart cultures, suggesting a cardioprotective mechanism against hypoxia.
Life sciences
El-Ani D,Zimlichman R,Mashiach Y,Shainberg A
Thu Aug 16 00:00:00 UTC 2007
Prothymosin alpha lacking the nuclear localization signal as an effective gene therapeutic strategy in collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Shiau AL,Chen SY,Chang MY,Su CH,Chung SY,Yo YT,Wang CR,Wu CL
Sun Apr 01 00:00:00 UTC 2007
System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes.
Journal of immunology (Baltimore, Md. : 1950)
Domercq M,Sánchez-Gómez MV,Sherwin C,Etxebarria E,Fern R,Matute C
Tue May 15 00:00:00 UTC 2007
TNF-alpha downregulates transient outward potassium current in rat ventricular myocytes through iNOS overexpression and oxidant species generation.
American journal of physiology. Heart and circulatory physiology
Fernández-Velasco M,Ruiz-Hurtado G,Hurtado O,Moro MA,Delgado C
Sun Jul 01 00:00:00 UTC 2007
Differential transcriptional control of the superoxide dismutase-2 kappaB element in neurons and astrocytes.
The Journal of biological chemistry
Mao X,Moerman-Herzog AM,Wang W,Barger SW
Fri Nov 24 00:00:00 UTC 2006
Cytokine regulation of skeletal muscle fatty acid metabolism: effect of interleukin-6 and tumor necrosis factor-alpha.
American journal of physiology. Endocrinology and metabolism
Bruce CR,Dyck DJ
Fri Oct 01 00:00:00 UTC 2004
Beneficial autoimmunity to proinflammatory mediators restrains the consequences of self-destructive immunity.
Immunity
Wildbaum G,Nahir MA,Karin N
Sat Nov 01 00:00:00 UTC 2003
Tenascin-R is antiadhesive for activated microglia that induce downregulation of the protein after peripheral nerve injury: a new role in neuronal protection.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Angelov DN,Walther M,Streppel M,Guntinas-Lichius O,Neiss WF,Probstmeier R,Pesheva P
Sat Aug 15 00:00:00 UTC 1998
