ALKBH2 Antibodies

Antibodies that detect ALKBH2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target ALKBH2 in Human, Mouse and Rat samples. Our ALKBH2 polyclonal antibodies are developed in Rabbit. Find the ALKBH2... Antibodies that detect ALKBH2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target ALKBH2 in Human, Mouse and Rat samples. Our ALKBH2 polyclonal antibodies are developed in Rabbit. Find the ALKBH2 antibody that fits your needs.... Antibodies that detect ALKBH2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target ALKBH2 in Human, Mouse and Rat samples. Our ALKBH2 polyclonal antibodies are developed in Rabbit. Find the ALKBH2 antibody that fits your needs. Choose from 1 of 6 ALKBH2 antibodies, which have been validated in experiments with 9 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to... Antibodies that detect ALKBH2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target ALKBH2 in Human, Mouse and Rat samples. Our ALKBH2 polyclonal antibodies are developed in Rabbit. Find the ALKBH2 antibody that fits your needs. Choose from 1 of 6 ALKBH2 antibodies, which have been validated in experiments with 9 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The E. coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells. Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation. Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer. Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.

Synonyms

2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

ALKBH2 Antibodies

Target Information

Synonyms

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