NUDT16 Antibodies

Antibodies that detect NUDT16 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target NUDT16 in Human and Mouse samples. Our NUDT16 polyclonal antibodies are developed in Rabbit.... Antibodies that detect NUDT16 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target NUDT16 in Human and Mouse samples. Our NUDT16 polyclonal antibodies are developed in Rabbit. Find the NUDT16 antibody that fits... Antibodies that detect NUDT16 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target NUDT16 in Human and Mouse samples. Our NUDT16 polyclonal antibodies are developed in Rabbit. Find the NUDT16 antibody that fits your needs. Choose from 1 of 6 NUDT16 antibodies, which have been validated in experiments with 4 publications and 12 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're... Antibodies that detect NUDT16 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target NUDT16 in Human and Mouse samples. Our NUDT16 polyclonal antibodies are developed in Rabbit. Find the NUDT16 antibody that fits your needs. Choose from 1 of 6 NUDT16 antibodies, which have been validated in experiments with 4 publications and 12 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and/or m227G caps from U8 snoRNA and leaves a 5'monophosphate on the RNA. Catalyzes also the cleavage of the cap structure on mRNAs. Does not hydrolyze cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG). Also hydrolysis m7G- and m227G U3-capped RNAs but with less efficiencies. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species. Binds to the U8 snoRNA; metal is not required for RNA-binding. May play a role in the regulation of snoRNAs and mRNAs degradation. Acts also as a phosphatase; hydrolyzes the non-canonical purine nucleotides inosine diphosphate (IDP) and deoxyinosine diphosphate (dITP) as well as guanosine diphosphate (GDP), deoxyguanosine diphosphate (dGDP), xanthine diphosphate (XDP), inosine triphosphate (ITP) and deoxyinosine triphosphate (ITP) to their respective monophosphate derivatives and does not distinguish between the deoxy- and ribose forms (PubMed:20385596, PubMed:26121039). The order of activity with different substrates is IDP > dIDP >> GDP = dGDP > XDP = ITP = dITP (PubMed:20385596). Binds strongly to GTP, ITP and XTP. Participates in the hydrolysis of dIDP/IDP and probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (PubMed:20385596). [UniProt]

Synonyms

2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; m7GpppN-mRNA hydrolase; Nucleoside diphosphate-linked moiety X motif 16; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; NUDT16; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

NUDT16 Antibodies

Target Information

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