Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Search All
Search button Close
          • Order Status
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central
          • Primary Antibodies ›
          • by Target

          SIGIRR Antibodies

          Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and... Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and... Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SIGIRR antibody that fits your needs. Choose from 1 of 12 SIGIRR antibodies, which have been validated in experiments with 3 publications and 19 images featured in our data gallery.

          Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the...
          Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SIGIRR antibody that fits your needs. Choose from 1 of 12 SIGIRR antibodies, which have been validated in experiments with 3 publications and 19 images featured in our data gallery.

          Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

          Target Information

          SIGIRR (single Ig IL-1R-related molecule) is a novel member of the interleukin 1 receptor (IL-1R) superfamily. Although it shows the typical conserved motifs that characterize the IL-1R and Toll superfamily, it is structurally and functionally distinct from both. SIGIRR has only one Ig domain in its extracellular portion whereas the IL-1R family contains three Ig folds. An unusually long cytoplasmic domain is reminiscent of the structure of drosophila Toll, yet the SIGIRR peptide sequence is more closely related to IL-1RI. A chimera, in which the SIGIRR intracellular domain was fused to the IL-1R extracellular domain, did not activate NFkappaB unlike similar fusion proteins of other IL-1R related molecules. Phylogenetic data that suggest that the plasma membrane protein SIGIRR is a close functional relative of MyD88 in mammals.

          Synonyms

          AI256711; IL-1R8; MGC110992; Sigirr; single Ig and TIR domain containing; single Ig IL-1 receptor related protein; single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; single Ig IL-1R-related protein; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; TIR8; Toll/interleukin-1 receptor 8; UNQ301/PRO342

          View more
          View less
          • Search by
          • Products
          • Images
          • Epitopes
          • Panel Builder LinkTry our free panel design service
          Filters

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          Filters
          Filters
          Show Less
          +-2
          Clear All
          More
          Less
          11 results
          Target
          Details
          Application
          Price
          Compare
          11 results
          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (HL2007)
          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (HL2007)
          3
          Target
          Human
          Details
          Rabbit Recombinant Monoclonal
          Application
          WB IHC (P)
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-47255

          100 µL

          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (HL2008)
          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (HL2008)
          3
          Target
          Human Mouse Rat
          Details
          Rabbit Recombinant Monoclonal
          Application
          WB IHC (P)
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-50360

          100 µL

          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (010), PE
          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (010), PE
          2
          Target
          Human
          Details
          Rabbit Recombinant Monoclonal
          Application
          Flow
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-40972

          100 Tests

          Proteintech
          SIGIRR Polyclonal Antibody
          Proteintech
          SIGIRR Polyclonal Antibody
          1
          Target
          Human Mouse
          Details
          Rabbit Polyclonal
          Application
          WB
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # 27828-1-AP

          150 µL

          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (010)
          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (010)
          1
          Target
          Human
          Details
          Rabbit Recombinant Monoclonal
          Application
          Flow
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-36024

          100 µL

          Invitrogen
          SIGIRR Polyclonal Antibody
          Invitrogen
          SIGIRR Polyclonal Antibody
          3
          Target
          Human Mouse
          Details
          Rabbit Polyclonal
          Application
          WB IHC (P) ELISA
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # PA5-98507

          100 µL

          Invitrogen
          SIGIRR Polyclonal Antibody
          Invitrogen
          SIGIRR Polyclonal Antibody
          2
          Target
          Human Mouse
          Details
          Rabbit Polyclonal
          Application
          WB ICC/IF
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # PA5-20078

          100 µg

          Invitrogen
          SIGIRR Polyclonal Antibody
          Invitrogen
          SIGIRR Polyclonal Antibody
          1
          Target
          Human Mouse
          Details
          Rabbit Polyclonal
          Application
          WB
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # PA1-41406

          100 µg

          Abnova
          SIGIRR Monoclonal Antibody (3H8-2G3)
          Abnova
          SIGIRR Monoclonal Antibody (3H8-2G3)
          1
          Target
          Human
          Details
          Mouse Monoclonal
          Application
          WB ELISA
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # H00059307-M01A

          200 µL

          Abnova
          SIGIRR Polyclonal Antibody, MaxPab™
          Abnova
          SIGIRR Polyclonal Antibody, MaxPab™
          1
          Target
          Human
          Details
          Rabbit Polyclonal
          Application
          WB
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # H00059307-D01P

          100 µg

          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (016)
          Invitrogen
          SIGIRR Recombinant Rabbit Monoclonal Antibody (016)
          Target
          Human
          Details
          Rabbit Recombinant Monoclonal
          Application
          ELISA
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-30876

          100 µL

          Custom Antibody Service

          Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.

          More than 18,000 custom antibodies created so far.

          Talk to a specialist now
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us
          • Careers
          • Investors
          • News
          • Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-67c77f6dc7-n6nf2:80/100.66.135.186:80.
          git-commit: 545e792480003146e539d624bd2a21b51d198228
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.31.0-2025.06.23-1.0