SMURF1 Antibodies

Antibodies that detect SMURF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target SMURF1 in Human, Mouse and Rat samples. Our SMURF1 polyclonal and monoclonal antibodies are... Antibodies that detect SMURF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target SMURF1 in Human, Mouse and Rat samples. Our SMURF1 polyclonal and monoclonal antibodies are developed in Rabbit and... Antibodies that detect SMURF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target SMURF1 in Human, Mouse and Rat samples. Our SMURF1 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SMURF1 antibody that fits your needs. Choose from 1 of 14 SMURF1 antibodies, which have been validated in experiments with 14 publications and 33 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen... Antibodies that detect SMURF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target SMURF1 in Human, Mouse and Rat samples. Our SMURF1 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SMURF1 antibody that fits your needs. Choose from 1 of 14 SMURF1 antibodies, which have been validated in experiments with 14 publications and 33 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Members of the transforming growth factor-beta (TGFB) family signal through type I and type II serine/threonine-kinase receptors, which in turn activate the SMAD signaling pathway. Bone morphogenetic protein (BMP) receptors target SMAD1, SMAD5, and SMAD8, whereas receptors for activin and TGFB (e. g., ACVR1 and TGFBR1, respectively) target SMAD2 and SMAD3. Phosphorylation of these receptor-regulated SMADs induces their association with the common-partner SMAD, SMAD4. Smurf1, a HECT domain E3 ubiquitin ligase, regulates cell polarity and protrusive activity and is required to maintain the transformed morphology and motility of a tumor cell. Atypical protein kinase C-zeta (PKC2), an effector of the Cdc42/Rac1-PAR6 polarity complex, recruits Smurf1 to cellular protrusions, where it controlled the local level of RhoA. Smurf1 thus links the polarity complex to degradation of RhoA in lamellipodia and filopodia to prevent RhoA signaling during dynamic membrane movements.

Synonyms

4930431E10Rik; E3 ubiquitin ligase SMURF1; E3 ubiquitin-protein ligase SMURF1; HECT-type E3 ubiquitin transferase SMURF1; hSMURF1; hSMURF2; KIAA1625; mKIAA1625; RGD1309707; SMAD specific E3 ubiquitin protein ligase 1; Smad ubiquitination regulatory factor 1; Smad-specific E3 ubiquitin ligase 1; SMAD-specific E3 ubiquitin-protein ligase 1; Smurf1

SMURF1 Antibodies

Target Information

Synonyms

Custom Antibody Service

Performance Guarantee

We're here to help

Your items have has been added!