TAB2 Antibodies

Antibodies that detect TAB2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target TAB2 in Human, Mouse, Rat and Non-human primate samples. Our TAB2 polyclonal,... Antibodies that detect TAB2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target TAB2 in Human, Mouse, Rat and Non-human primate samples. Our TAB2 polyclonal, monoclonal and recombinant... Antibodies that detect TAB2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target TAB2 in Human, Mouse, Rat and Non-human primate samples. Our TAB2 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the TAB2 antibody that fits your needs. Choose from 1 of 15 TAB2 antibodies, which have been validated in experiments with 17 publications and 26 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to... Antibodies that detect TAB2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target TAB2 in Human, Mouse, Rat and Non-human primate samples. Our TAB2 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the TAB2 antibody that fits your needs. Choose from 1 of 15 TAB2 antibodies, which have been validated in experiments with 17 publications and 26 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

TAB2 is an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation NF-kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Recent experiments have shown that TAB2 and the related protein TAB3 constitutively interact with the autophagy mediator Beclin-1; upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.

Synonyms

1110030N06Rik; A530078N03Rik; CHTD2; FLJ21885; KIAA0733; Map3k7ip2; mitogen activated protein kinase kinase kinase 7 interacting protein 2; mitogen-activated protein kinase kinase kinase 7 interacting protein 2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; mKIAA0733; OTTHUMP00000017388; TAB2; TAB-2; Tak1 binding protein 2; TAK1-binding protein 2; TGF-beta activated kinase 1/MAP3K7 binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1-binding protein 2

TAB2 Antibodies

Target Information

Synonyms

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