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Invitrogen
14-3-3 eta Polyclonal Antibody
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FIGURE: 1 / 2
14-3-3 eta Antibody (PA5-101280) in ICC/IF
Immunocytochemistry analysis of 14-3-3 eta in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with 14-3-3 eta polyclonal antibody (Product # PA5-101280) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated... View More
Product Details
PA5-101280
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human YWHAH(Accession Q04917), corresponding to amino acid residues K127-L177.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850719
Product Specific Information
Antibody detects endogenous levels of total 14-3-3 eta.
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14-3-3 eta; 14-3-3 protein eta; 14-3-3 protein eta-subtype; 1433F; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA114-3-3 eta
Gene Aliases: 14-3-3e; YWHA1; YWHAH
UniProt ID: (Human) Q04917, (Rat) P68511, (Mouse) P68510
Entrez Gene ID: (Human) 7533, (Rat) 25576, (Mouse) 22629
regulation of sodium ion transport
glucocorticoid catabolic process
intracellular protein transport
substantia nigra development
glucocorticoid receptor signaling pathway
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
membrane organization
membrane depolarization during action potential
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of sodium ion transmembrane transporter activity
biological_process
cytoskeleton organization
regulation of mitotic nuclear division
negative regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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