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5HT1A R Polyclonal Antibody
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Product Details
OSS00228W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 300-350 of mouse 5HT1A R conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide shares 96% identity with rat and human sequences.
Specificity of this antibody: 5HT1A receptor.
Target Information
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5-HT-1A; 5-HT1A receptor; 5-hydroxytryptamine receptor 1A; G-protein coupled receptor 18; Serotonin receptor 1A
Gene Aliases: Gpcr18; Htr1a
UniProt ID: (Mouse) Q64264
Entrez Gene ID: (Mouse) 15550
behavioral fear response
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
serotonin receptor signaling pathway
behavior
cell proliferation
regulation of serotonin secretion
positive regulation of microtubule depolymerization
exploration behavior
regulation of dopamine metabolic process
vasoconstriction
serotonin metabolic process
regulation of hormone secretion
regulation of behavior
regulation of feeding behavior
NMDA glutamate receptor clustering
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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