Osenses

5HT1E R Polyclonal Antibody

Product Details

OSS00186W-100UL

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

Immunohistochemistry (IHC)

1:300-1:2,000

Miscellaneous PubMed (MISC)

View 6 publications 6 publications

Product Specifications

Species Reactivity

Guinea pig, Human

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from c-terminal region of human 5HT1E receptor (Serotonin receptor 1E) conjugated to an immunogenic carrier protein was used as the antigen

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: 5HT1E receptor.

Target Information

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Human-specific amino acid changes found in 103 protein-coding genes.

Molecular biology and evolution

Kitano T,Liu YH,Ueda S,Saitou N

Sat May 01 00:00:00 UTC 2004

Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor.

European journal of pharmacology

Bai F,Yin T,Johnstone EM,Su C,Varga G,Little SP,Nelson DL

Mon Jan 26 00:00:00 UTC 2004

The DNA sequence and analysis of human chromosome 6.

Nature

Mungall AJ,Palmer SA,Sims SK,Edwards CA,Ashurst JL,Wilming L,Jones MC,Horton R,Hunt SE,Scott CE,Gilbert JG,Clamp ME,Bethel G,Milne S,Ainscough R,Almeida JP,Ambrose KD,Andrews TD,Ashwell RI,Babbage AK,Bagguley CL,Bailey J,Banerjee R,Barker DJ,Barlow KF,Bates K,Beare DM,Beasley H,Beasley O,Bird CP,Blakey S,Bray-Allen S,Brook J,Brown AJ,Brown JY,Burford DC,Burrill W,Burton J,Carder C,Carter NP,Chapman JC,Clark SY,Clark G,Clee CM,Clegg S,Cobley V,Collier RE,Collins JE,Colman LK,Corby NR,Coville GJ,Culley KM,Dhami P,Davies J,Dunn M,Earthrowl ME,Ellington AE,Evans KA,Faulkner L,Francis MD,Frankish A,Frankland J,French L,Garner P,Garnett J,Ghori MJ,Gilby LM,Gillson CJ,Glithero RJ,Grafham DV,Grant M,Gribble S,Griffiths C,Griffiths M,Hall R,Halls KS,Hammond S,Harley JL,Hart EA,Heath PD,Heathcott R,Holmes SJ,Howden PJ,Howe KL,Howell GR,Huckle E,Humphray SJ,Humphries MD,Hunt AR,Johnson CM,Joy AA,Kay M,Keenan SJ,Kimberley AM,King A,Laird GK,Langford C,Lawlor S,Leongamornlert DA,Leversha M,Lloyd CR,Lloyd DM,Loveland JE,Lovell J,Martin S,Mashreghi-Mohammadi M,Maslen GL,Matthews L,McCann OT,McLaren SJ,McLay K,McMurray A,Moore MJ,Mullikin JC,Niblett D,Nickerson T,Novik KL,Oliver K,Overton-Larty EK,Parker A,Patel R,Pearce AV,Peck AI,Phillimore B,Phillips S,Plumb RW,Porter KM,Ramsey Y,Ranby SA,Rice CM,Ross MT,Searle SM,Sehra HK,Sheridan E,Skuce CD,Smith S,Smith M,Spraggon L,Squares SL,Steward CA,Sycamore N,Tamlyn-Hall G,Tester J,Theaker AJ,Thomas DW,Thorpe A,Tracey A,Tromans A,Tubby B,Wall M,Wallis JM,West AP,White SS,Whitehead SL,Whittaker H,Wild A,Willey DJ,Wilmer TE,Wood JM,Wray PW,Wyatt JC,Young L,Younger RM,Bentley DR,Coulson A,Durbin R,Hubbard T,Sulston JE,Dunham I,Rogers J,Beck S

Thu Oct 23 00:00:00 UTC 2003

Characterization of single-nucleotide polymorphisms in coding regions of human genes.

Nature genetics

Cargill M,Altshuler D,Ireland J,Sklar P,Ardlie K,Patil N,Shaw N,Lane CR,Lim EP,Kalyanaraman N,Nemesh J,Ziaugra L,Friedland L,Rolfe A,Warrington J,Lipshutz R,Daley GQ,Lander ES

Thu Jul 01 00:00:00 UTC 1999

Assignment of the gene encoding the 5-HT1E serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15.

Genomics

Levy FO,Holtgreve-Grez H,Taskén K,Solberg R,Ried T,Gudermann T

Mon Aug 01 00:00:00 UTC 1994

Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor.

Molecular pharmacology

Zgombick JM,Schechter LE,Macchi M,Hartig PR,Branchek TA,Weinshank RL

Sat Aug 01 00:00:00 UTC 1992

Bioinformatics

Protein Aliases: 5-HT-1E; 5-HT1E; 5-HT1e receptor; 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled; 5-hydroxytryptamine receptor 1E; 5HT1E Receptor; HT1e receptor; S31; Serotonin receptor 1E

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Gene Aliases: 5-HT1E; 5HT1E; HTR1E

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UniProt ID: (Human) P28566, (Guinea pig) Q6VB83

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Entrez Gene ID: (Human) 3354, (Guinea pig) 100379275

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Function(s)

G-protein coupled receptor activity G-protein coupled serotonin receptor activity protein binding serotonin binding

Process(es)

G-protein coupled receptor signaling pathway G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway serotonin receptor signaling pathway chemical synaptic transmission negative regulation of cAMP metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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5HT1E R Polyclonal Antibody

Product Details

OSS00186W-100UL

Western Blot (WB)

Immunohistochemistry (IHC)

Miscellaneous PubMed (MISC)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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