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5HT3D R/5HT3E R Polyclonal Antibody
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Product Details
OSS00194W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from c-terminal region of human 5HT3D receptor (Serotonin receptor 3D) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in 5HT3E.
Specificity of this antibody: 5HT3D, 5HT3E receptors.
Target Information
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Subcellular Location: Cell membrane; Multi-pass membrane protein. Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. Tissue Specificity: 5HT3D: Expressed in liver, as well as fetal and adult colon and kidney. 5HT3E: Expressed in adult colon and intestine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5-HT-1E; 5-HT3-D; 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled; 5-hydroxytryptamine (serotonin) receptor 3 family member D; 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic; 5-hydroxytryptamine receptor 1E; 5-hydroxytryptamine receptor 3 subunit D; 5-hydroxytryptamine receptor 3D; S31; serotonin 5-HT-3D receptor; Serotonin receptor 1E; Serotonin receptor 3D
Gene Aliases: 5-HT1E; 5HT3D; HTR1E; HTR3D
UniProt ID: (Human) P28566, (Human) Q70Z44
Entrez Gene ID: (Human) 3354, (Human) 200909
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
serotonin receptor signaling pathway
chemical synaptic transmission
negative regulation of cAMP metabolic process
synaptic transmission, cholinergic
ion transmembrane transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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