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Product Details
H00008086-M02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
5A1
Immunogen
AAAS (NP_056480, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MCSLGLFPPP PPRGQVTLYE HNNELVTGSS YESPPPDFRG QWINLPVLQL TKDPLKTPGR LDHGTRTAFI HHREQVWKRC INIWRDVGLF GVLNEIANSE
Target Information
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: achalasia, adrenocortical insufficiency, alacrimia; achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A); Adracalin; Aladin; Allgrove, triple-A
Gene Aliases: AAA; AAAS; AAASb; ADRACALA; ADRACALIN; ALADIN; D030041N15Rik; GL003
UniProt ID: (Human) Q9NRG9, (Mouse) P58742
Entrez Gene ID: (Human) 8086, (Mouse) 223921, (Rat) 300259
mRNA export from nucleus
tRNA export from nucleus
nucleocytoplasmic transport
mitotic nuclear envelope disassembly
learning
fertilization
regulation of glucose transport
protein transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
regulation of nucleocytoplasmic transport
intracellular transport of virus
regulation of cellular response to heat
transport
mRNA transport
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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