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Proteintech
AARE Polyclonal Antibody
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Product Details
14758-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AARE Fusion Protein Ag6511 (381-732 aa encoded by BC000362)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize at least 2 isoforms of APH.
Immunogen sequence: AQRSRQDLF AVDTQVGTVT SLTAGGSGGS WKLLTIDQDL MVAQFSTPSL PPTLKVGFLP SAGKEQSVLW VSLEEAEPIP DIHWGIRVLQ PPPEQENVQY AGLDFEAILL QPGSPPDKTQ VPMVVMPHGG PHSSFVTAWM LFPAMLCKMG FAVLLVNYRG STGFGQDSIL SLPGNVGHQD VKDVQFAVEQ VLQEEHFDAS HVALMGGSHG GFISCHLIGQ YPETYRACVA RNPVINIASM LGSTDIPDWC VVEAGFPFSS DCLPDLSVWA EMLDKSPIRY IPQVKTPLLL MLGQEDRRVP FKQGMEYYRA LKTRNVPVRL LLYPKSTHAL SEVEVESDSF MNAVLWLRTH LGS (381-732 aa encoded by BC000362)
Target Information
APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AARE; Acyl-peptide hydrolase; Acylamino-acid-releasing enzyme; Acylaminoacyl-peptidase; acylpeptide hydrolase; APH; MGC2178; N-acylaminoacyl peptide hydrolase; N-acylaminoacyl-peptide hydrolase; OPH; Oxidized protein hydrolase
Gene Aliases: AARE; ACPH; APEH; APH; D3F15S2; D3S48E; DNF15S2; OPH
UniProt ID: (Human) P13798, (Mouse) Q8R146, (Rat) P13676
Entrez Gene ID: (Human) 327, (Mouse) 235606, (Rat) 24206
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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