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NeoBiotechnologies
ABCC11/ATP Binding Cassette Subfamily C Member 11 Monoclonal Antibody (ABCC11/2438)
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ABCC11/ATP Binding Cassette Subfamily C Member 11 Antibody (85320-MSM2-P1) in IHC (P)
Formalin-fixed, paraffin-embedded human triple negative breast cancer stained with ABCC11 Mouse Monoclonal Antibody (ABCC11/2438). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.
Product Details
85320-MSM2-P1
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
ABCC11/2438
Immunogen
Recombinant fragment (around aa400-600) of human ABCC11 protein.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control:Human breast, breast cancer or testis.
Cellular Location: Membrane.
Target Information
ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-binding cassette protein C11; ATP-binding cassette sub-family C member 11; ATP-binding cassette transporter MRP8; ATP-binding cassette transporter sub-family C member 11; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; multi-resistance protein 8; Multidrug resistance-associated protein 8
Gene Aliases: ABCC11; EWWD; MRP8; WW
UniProt ID: (Human) Q96J66
Entrez Gene ID: (Human) 85320
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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