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ABCC6 Antibody (PA5-103933) in IHC (P)
Immunohistochemistry analysis of ABCC6 in mouse kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ABCC6 polyclonal antibody (Product # PA5-103933) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103933
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ABCC6(Accession O95255), corresponding to amino acid residues L316-F366.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2853265
Product Specific Information
Antibody detects endogenous levels of total MRP6.
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anthracycline resistance-associated protein; ATP-binding cassette sub-family C member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C, member 6; liver multidrug resistance-associated protein 6; MLP-1; MOAT-E; MRP-like protein 1; Multi-specific organic anion transporter E; Multidrug resistance-associated protein 6; multidrug resistance-associated protein-6
Gene Aliases: ABC34; Abcc1b; ABCC6; ARA; DCC; dyscalc; Dyscalc1; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
UniProt ID: (Human) O95255, (Mouse) Q9R1S7, (Rat) O88269
Entrez Gene ID: (Human) 368, (Mouse) 27421, (Rat) 81642
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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