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Invitrogen
ABO Recombinant Rabbit Monoclonal Antibody (23GB3610)
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FIGURE: 1 / 1
ABO Antibody (MA5-52620) in WB
Western Blot analysis of ABO. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with ABO recombinant monoclonal antibody (Product # MA5-52620) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit.
Product Details
MA5-52620
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB3610
Immunogen
A synthetic peptide of human BGAT (5-28AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3249097
Target Information
Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene. The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A transferase; A1-specific alpha 1-3-N-acetylgalactosaminyltransferase; ABO A3 transferase; ABO blood group (alpha 1-3-N-acetylgalactosaminyltransferase, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; ABO weak transfer; B (A) alpha 1; B blood group galactosyltransferase; B transferase; B(A) alpha-1,3-galactosyltransferase; BGAT; Blood group A glycosyltransferase 2; Cis-AB transferase; Cis-AB transferase 2; fucosylglycoprotein; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; glycosyltransferase A; glycosyltransferase B; Histo-blood group A transferase; histo-blood group A2 transferase; Histo-blood group ABO system transferase; Histo-blood group ABO system transferase 2; Histo-blood group B transferase; NAGAT; NAGAT 2; Putative blood group A transferase T2; Transferase; transferase A; transferase B, alpha 1-3-galactosyltransferase)
Gene Aliases: A3GALNT; A3GALT1; ABO; Abo2; GTB; NAGAT
UniProt ID: (Human) P16442, (Mouse) P38649, (Rat) Q8CFC4
Entrez Gene ID: (Human) 28, (Mouse) 80908, (Rat) 100301568
glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity
fucosylgalactoside 3-alpha-galactosyltransferase activity
metal ion binding
alpha-1,3-galactosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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