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Invitrogen
ACER2 Polyclonal Antibody
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Product Details
PA5-75832
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human ACER2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719560
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acylsphingosine deacylase 3-like; alkaline CDase 2; Alkaline ceramidase 2; AlkCDase 2; ceramide hydrolase; haCER2; N-acylsphingosine amidohydrolase 3-like
Gene Aliases: ACER2; ALKCDase2; ASAH3L; PP11646
UniProt ID: (Human) Q5QJU3
Entrez Gene ID: (Human) 340485, (Rat) 313339
negative regulation of cell-matrix adhesion
ceramide metabolic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell proliferation
positive regulation of cell death
sphingolipid biosynthetic process
response to retinoic acid
negative regulation of cell adhesion mediated by integrin
cellular response to drug
sphingosine biosynthetic process
negative regulation of protein glycosylation in Golgi
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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