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          • Primary Antibodies ›
          • ACOX1 Antibodies

          Proteintech

          ACOX1 Polyclonal Antibody

          76 References
          View all (16) ACOX1 antibodies

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          Cite ACOX1 Polyclonal Antibody

          • Antibody Testing Data (10)
          ACOX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          ACOX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          ACOX1 Antibody (10957-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using (Product # 10957-1-AP) (ACOX1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ACOX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ACOX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ACOX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ACOX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ACOX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ACOX1 Antibody in Western Blot (WB)
          ACOX1 Antibody in Western Blot (WB)
          ACOX1 Antibody in Western Blot (WB)
          ACOX1 Antibody in Western Blot (WB)
          ACOX1 Antibody in Western Blot (WB)

          Product Details

          10957-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 60 publications 60 publications

          Immunohistochemistry (IHC)

          -
          View 8 publications 8 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 5 publications 5 publications

          Miscellaneous PubMed (MISC)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          ACOX1 Fusion Protein Ag1405 (275-660 aa encoded by BC010425)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: YGTMVFVRS FLVGEAARAL SKACTIAIRY SAVRHQSEMK PGEPEPQILD FQTQQYKLFP LLATAYAFQF VGAYMKETYH RINEGIGQGD LSELPELHAL TAGLKAFTSW TANTGIEACR MACGGHGYSH CSGLPNIYVN FTPSCTFEGE NTVMMLQTAR FLMKSYDQVH SGKLVCGMVS YLNDLPSQRI QPQQVAVWPT MVDINSPESL TEAYKLRAAR LVEIAAKNLQ KEVIHRKSKE VAWNLTSVDL VRASEAHCHY VVVKLFSEKL LKIQDKAIQA VLRSLCLLYS LYGISQNAGD FLQGSIMTEP QITQVNQRVK ELLTLIRSDA VALVDAFDFQ DVTLGSVLGR YDGNVYENLF EWAKNSPLNK AEVHESYKHL KSLQSKL (275-660 aa encoded by BC010425 )

          Target Information

          The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: ACO; acyl-CoA oxidase 1, palmitoyl; acyl-CoA oxidase, straight-chain; acyl-Coenzyme A oxidase 1, palmitoyl; AOX; Palmitoyl-CoA oxidase; Peroxisomal acyl-coenzyme A oxidase 1; Peroxisomal fatty acyl-CoA oxidase; peroxisomal fatty acyl-coenzyme A oxidase; peroxisomal straight-chain Acyl-CoA oxidase; SCOX; Straight-chain acyl-CoA oxidase

          View more View less

          Gene Aliases: ACOX; ACOX1; AOX; D130055E20Rik; PALMCOX; Paox; RATACOA1; SCOX

          View more View less

          UniProt ID: (Human) Q15067, (Rat) P07872, (Mouse) Q9R0H0

          View more View less

          Entrez Gene ID: (Human) 51, (Rat) 50681, (Mouse) 11430

          View more View less

          Function(s)
          fatty-acyl-CoA binding acyl-CoA dehydrogenase activity acyl-CoA oxidase activity receptor binding electron carrier activity PDZ domain binding protein N-terminus binding flavin adenine dinucleotide binding oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor fatty acid binding palmitoyl-CoA oxidase activity FAD binding oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors
          Process(es)
          very long-chain fatty acid metabolic process generation of precursor metabolites and energy lipid metabolic process fatty acid beta-oxidation prostaglandin metabolic process spermatogenesis peroxisome fission fatty acid oxidation fatty acid beta-oxidation using acyl-CoA oxidase lipid homeostasis positive regulation of cholesterol homeostasis fatty acid metabolic process metabolic process oxidation-reduction process fatty acid beta-oxidation using acyl-CoA dehydrogenase alpha-linolenic acid metabolic process
          It has to be done as per old AB suggested Products section.
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