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Immunogen sequence: YRGGYFSGEQ AGEVLESAVL ALCSQLKDDA VALVDVIAPP DFVLDSPIGR ADGELYKNLW GAVLQESKVL ERASWWPEFS VNKPVIGSLK SKL
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 75%.
Acyl-Coenzyme A oxidase 3 also know as pristanoyl-CoA oxidase (ACOX3) is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acyl-Coenzyme A oxidase 3, pristanoyl; Branched-chain acyl-CoA oxidase; BRCACox; Peroxisomal acyl-coenzyme A oxidase 3; Pristanoyl-CoA oxidase
Gene Aliases: ACOX3; BRCOX; PRCOX
UniProt ID: (Human) O15254
Entrez Gene ID: (Human) 8310
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