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Immunogen sequence: LVHKWAWTK DDVILHVLPL HHVHGVVNAL LCPLWVGATC VMMPEFSPQQ VWEKFLSSET PRINVFMAVP TIYTKLMEYY DRHFTQPHAQ DFLRAVCEEK IRLMVSGSAA LPLPVLEKWK NITGHTLLER YGMTEIGMAL SGPLTTAMRL PGSVGTPLPG VQVRIVSENP QREACSYTIH AEGDERGTKV TPGFEEKEGE LLVRGPSVFR EYWNKPEETK SAFTLDGWFK TGDTVVFKDG QYWIRGRTSV DIIKTGGYKV SALEVEWHLL AHPSITDVAV IGVPDMTWGQ RVTAVVTLRE GHSLSHRELK EWARNVLAPY AVPSELVLVE EIPRNQMGKI DKKALIRHFH PS (226-576 aa encoded by BC028399)
Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acyl-CoA synthetase family member 3; acyl-CoA synthetase family member 3, mitochondrial; Malonate--CoA ligase ACSF3, mitochondrial; malonyl-CoA synthetase
Gene Aliases: ACSF3; BB101783; PSEC0197
UniProt ID: (Human) Q4G176, (Mouse) Q3URE1
Entrez Gene ID: (Human) 197322, (Mouse) 257633
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