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Invitrogen
ACSL1 Monoclonal Antibody (A9B5)
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ACSL1 Antibody (MA5-50618) in IHC (P)
Immunohistochemistry of ACSL1 in paraffin-embedded mouse heart tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with ACSL1 monoclonal antibody (Product # MA5-50618) with a dilution of 1:1,000 for 1 hour at room temperature. ... View More
Product Details
MA5-50618
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
A9B5
Immunogen
Recombinant protein within human aa 151-350/698.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3094011
Product Specific Information
Positive control: Rat kidney tissue, human liver tissue, mouse heart tissue, Raji cell lysate, HepG2 cell lysate, LO2 cell lysate, A431 cell lysate.
Predicted band size: 78 kDa
Subcellular Location: Mitochondrion outer membrane, Peroxisome membrane, Microsome membrane, Endoplasmic reticulum membrane.
Target Information
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACS1; Acyl CoA synthetase, long chain; Acyl-CoA synthetase 1; Arachidonate--CoA ligase; fatty acid Coenzyme A ligase, long chain 2; fatty-acid-Coenzyme A ligase, long-chain 1; fatty-acid-Coenzyme A ligase, long-chain 2; L LACS2; LACS 1; LACS 2; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 1; Long-chain acyl-CoA synthetase 2; Long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; Long-chain-fatty-acid--CoA ligase 1; Long-chain-fatty-acid--CoA ligase, liver isozyme; OTTHUMP00000218457; OTTHUMP00000218460; OTTHUMP00000218462; OTTHUMP00000218465; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1; Phytanate--CoA ligase
Gene Aliases: Acas; Acas1; ACS; ACS1; ACSL1; Acsl2; COAA; FACL1; FACL2; FACS; LACS; LACS 1; LACS1; LACS2
UniProt ID: (Human) P33121, (Mouse) P41216, (Rat) P18163
Entrez Gene ID: (Human) 2180, (Mouse) 14081, (Rat) 25288
long-chain fatty acid metabolic process
triglyceride metabolic process
response to nutrient
lipid biosynthetic process
response to organic cyclic compound
fatty acid transport
adiponectin-activated signaling pathway
response to oleic acid
long-chain fatty-acyl-CoA biosynthetic process
alpha-linolenic acid metabolic process
xenobiotic catabolic process
response to drug
linoleic acid metabolic process
long-chain fatty acid import
positive regulation of protein serine/threonine kinase activity
lipid metabolic process
fatty acid metabolic process
response to organic substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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