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Product Details
17355-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ACTL7A Fusion Protein Ag10613 (1-280 aa encoded by BC014610)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MWAPPAAIM GDGPTKKVGN QAPLQTQALQ TASLRDGPAK RAVWVRHTSS EPQEPTESKA AKERPKQEVT KAVVVDLGTG YCKCGFAGLP RPTHKISTTV GKPYMETAKT GDNRKETFVG QELNNTNVHL KLVNPLRHGI IVDWDTVQDI WEYLFRQEMK IAPEEHAVLV SDPPLSPHTN REKYAEMLFE AFNTPAMHIA YQSRLSMYSY GRTSGLVVEV GHGVSYVVPI YEGYPLPSIT GRLDYAGSDL TAYLLGLLNS AGNEFTQDQM GIVEDIKKKC C (1-280 aa encoded by BC014610)
Target Information
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin-like 7-alpha; actin-like 7A; Actin-like protein 7A; actin-like Tact2; Actin-like-7-alpha; t-actin 2; T-actin-2; testicular secretory protein Li 3; Testis-specific actin-2
Gene Aliases: ACTL7A; Arp7a; T-actin 2; Tact2
UniProt ID: (Human) Q9Y615, (Mouse) Q9QY84, (Rat) Q641W9
Entrez Gene ID: (Human) 10881, (Mouse) 11470, (Rat) 298017
Performance Guarantee
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