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          • Primary Antibodies ›
          • ADAM12 Antibodies

          Proteintech

          ADAM12 Polyclonal Antibody

          53 References
          View all (19) ADAM12 antibodies

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          Datasheet
          Protocols
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          Datasheet
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          Cite ADAM12 Polyclonal Antibody

          • Antibody Testing Data (18)
          ADAM12 Antibody in Immunocytochemistry (ICC/IF)
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          ADAM12 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 18

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          ADAM12 Antibody (14139-1-AP) in ICC/IF

          Immunofluorescent analysis of HepG2 cells, using ADAM12 antibody 14139-1-AP at 1:25 and Rhodamine-labeled goat anti-rabbit IGG (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ADAM12 Antibody in Immunocytochemistry (ICC/IF)
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Western Blot (WB)
          ADAM12 Antibody in Immunoprecipitation (IP)

          Product Details

          14139-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 24 publications 24 publications

          Immunohistochemistry (IHC)

          -
          View 15 publications 15 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 7 publications 7 publications

          Flow Cytometry (Flow)

          Assay-dependent
          View 2 publications 2 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication

          Miscellaneous PubMed (MISC)

          -
          View 2 publications 2 publications

          Not applicable (N/A)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          ADAM12 Fusion Protein Ag5206 (31-350 aa encoded by BC060804)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.26 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody can recognize all isoforms of ADAM12. ADAM12 has 4 forms: 120 kDa full-length form, 90 kDa mature (processed form that lack the pro domain);50-68 kDa degradation product and 27 kDa pro domain.

          Immunogen sequence: VSLWNQGRA DEVVSASVRS GDLWIPVKSF DSKNHPEVLN IRLQRESKEL IINLERNEGL IASSFTETHY LQDGTDVSLA RNYTGHCYYH GHVRGYSDSA VSLSTCSGLR GLIVFENESY VLEPMKSATN RYKLFPAKKL KSVRGSCGSH HNTPNLAAKN VFPPPSQTWA RRHKRETLKA TKYVELVIVA DNREFQRQGK DLEKVKQRLI EIANHVDKFY RPLNIRIVLV GVEVWNDMDK CSVSQDPFTS LHEFLDWRKM KLLPRKSHDN AQLVSGVYFQ GTTIGMAPIM SMCTADQSGG IVMDHSDNPL GAAVTLAHEL G (31-350 aa encoded by BC060804)

          Target Information

          ADAM12 is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form is a soluble form lacking the transmembrane and cytoplasmic domains. The short form of ADAM12 was reported to provoke myogenesis, and the lack of cytoplasmic domain suggests different regulation pathways (although both forms can be expressed in the same tissue).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: a disintegrin and metalloprotease domain 12; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 12 (meltrin alpha); ADAM; ADAM 12; ADAMs; Disintegrin and metalloproteinase domain-containing protein 12; meltrin alpha; Meltrin-alpha; metalloendopeptidases; metalloprotease-disintegrin 12 transmembrane; PRO545; RP11-295J3.5; UNQ346

          View more View less

          Gene Aliases: ADAM12; ADAM12-OT1; CAR10; MCMP; MCMPMltna; mKIAA4001; MLTN; MLTNA; UNQ346/PRO545

          View more View less

          UniProt ID: (Human) O43184, (Mouse) Q61824

          View more View less

          Entrez Gene ID: (Human) 8038, (Mouse) 11489

          View more View less

          Function(s)
          metalloendopeptidase activity metallopeptidase activity zinc ion binding SH3 domain binding protein binding peptidase activity hydrolase activity metal ion binding
          Process(es)
          proteolysis cell adhesion myoblast fusion
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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