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Immunogen sequence: MWRVLFLLS GLGGLRMDSN FDSLPVQITV PEKIRSIIKE GIESQASYKI VIEGKPYTVN LMQKNFLPHN FRVYSYSGTG IMKPLDQDFQ NFCHYQGYIE GYPKSVVMVS TCTGLRGVLQ FENVSYGIEP LESSVGFEHV IYQVKHKKAD VSLYNEKDIE SRDLSFKLQS VEYNHMGSDT TVVAQKVFQL IGLTNAIFVS FNITIILSSL ELWIDENKIA TTGEANELLH TFLRWKTSYL VLRPHDVAFL LVYREKSNYV GATFQGKMCD ANYAGGVVLH PRTISLESLA VILAQLLSLS MGITYDDINK CQCSGAVCIM NPEAIHFSGV KIFSNCSFED FAHFISKQKS QCLH (1-353 aa encoded by BC034957)
ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloprotease domain 2 (fertilin beta); a disintegrin and metalloproteinase; ADAM; ADAM 2; ADAMs; Cancer/testis antigen 15; CT15; Disintegrin and metalloproteinase domain-containing protein 2; fertilin beta; Fertilin subunit beta; metalloendopeptidases; PH-30; PH30; PH30-beta
Gene Aliases: ADAM2; AI323749; CRYN1; CRYN2; CT15; FTNB; PH-30b; PH30; PH30-beta
UniProt ID: (Human) Q99965, (Mouse) Q60718
Entrez Gene ID: (Human) 2515, (Mouse) 11495
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