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          • Primary Antibodies ›
          • ADAM2 Antibodies

          Invitrogen

          ADAM2 Polyclonal Antibody

          View all (11) ADAM2 antibodies

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          Cite ADAM2 Polyclonal Antibody

          • Antibody Testing Data (1)
          ADAM2 Antibody in Western Blot (WB)
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          ADAM2 Antibody in Western Blot (WB)
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          FIGURE: 1 / 1

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          ADAM2 Antibody (PA5-87699) in WB

          Western blot analysis of ADAM2 in extracts of various cell lines. Samples were incubated with ADAM2 Polyclonal antibody (Product # PA5-87699) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ADAM2 Antibody in Western Blot (WB)

          Product Details

          PA5-87699

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 476-686 of human ADAM2 (Q99965)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.12 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Wet ice

          RRID

          AB_2804355

          Product Specific Information

          Positive Samples: HL-60, MCF7, Jurkat, Raji, Mouse testis, Rat testis; Cellular Location: Membrane, Single-pass type I membrane protein

          Immunogen sequence: PCGLNQWICI DGVCMSGDKQ CTDTFGKEVE FGPSECYSHL NSKTDVSGNC GISDSGYTQC EADNLQCGKL ICKYVGKFLL QIPRATIIYA NISGHLCIAV EFASDHADSQ KMWIKDGTSC GSNKVCRNQR CVSSSYLGYD CTTDKCNDRG VCNNKKHCHC SASYLPPDCS VQSDLWPGGS IDSGNFPPVA IPARLPERRY IENIYHSKPM R

          Target Information

          ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: a disintegrin and metallopeptidase domain 2; a disintegrin and metalloprotease domain 2; a disintegrin and metalloprotease domain (ADAM) 2; A disintegrin and metalloprotease domain 2 (Fertilin beta); a disintegrin and metalloproteinase; ADAM; ADAM 2; ADAMs; Cancer/testis antigen 15; CT15; Disintegrin and metalloproteinase domain-containing protein 2; fertilin beta; Fertilin subunit beta; metalloendopeptidases; PH-30; PH30; PH30-beta

          View more View less

          Gene Aliases: ADAM2; AI323749; CRYN1; CRYN2; CT15; FTNB; PH-30; PH-30b; PH30; PH30-beta

          View more View less

          UniProt ID: (Human) Q99965, (Rat) Q63202, (Mouse) Q60718

          View more View less

          Entrez Gene ID: (Human) 2515, (Rat) 56806, (Mouse) 11495

          View more View less

          Function(s)
          metalloendopeptidase activity integrin binding metallopeptidase activity zinc ion binding protein binding
          Process(es)
          proteolysis cell adhesion spermatogenesis visual learning fertilization adult behavior binding of sperm to zona pellucida fusion of sperm to egg plasma membrane
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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