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FIGURE: 1 / 1
Positive Samples: HL-60, MCF7, Jurkat, Raji, Mouse testis, Rat testis; Cellular Location: Membrane, Single-pass type I membrane protein
Immunogen sequence: PCGLNQWICI DGVCMSGDKQ CTDTFGKEVE FGPSECYSHL NSKTDVSGNC GISDSGYTQC EADNLQCGKL ICKYVGKFLL QIPRATIIYA NISGHLCIAV EFASDHADSQ KMWIKDGTSC GSNKVCRNQR CVSSSYLGYD CTTDKCNDRG VCNNKKHCHC SASYLPPDCS VQSDLWPGGS IDSGNFPPVA IPARLPERRY IENIYHSKPM R
ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metallopeptidase domain 2; a disintegrin and metalloprotease domain 2; a disintegrin and metalloprotease domain (ADAM) 2; A disintegrin and metalloprotease domain 2 (Fertilin beta); a disintegrin and metalloproteinase; ADAM; ADAM 2; ADAMs; Cancer/testis antigen 15; CT15; Disintegrin and metalloproteinase domain-containing protein 2; fertilin beta; Fertilin subunit beta; metalloendopeptidases; PH-30; PH30; PH30-beta
Gene Aliases: ADAM2; AI323749; CRYN1; CRYN2; CT15; FTNB; PH-30; PH-30b; PH30; PH30-beta
UniProt ID: (Human) Q99965, (Rat) Q63202, (Mouse) Q60718
Entrez Gene ID: (Human) 2515, (Rat) 56806, (Mouse) 11495
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