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Invitrogen
ADAM28 Polyclonal Antibody
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FIGURE: 1 / 1
ADAM28 Antibody (PA5-97223) in WB
Western blot analysis of ADAM28 in extracts of various cell lines. Samples were incubated with ADAM28 Polyclonal antibody (Product # PA5-97223) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-97223
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 199-440 of human ADAM28 (NP_0550802)
Conjugate
Form
Liquid
Concentration
4.09 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2809025
Product Specific Information
Immunogen sequence: VQEHEKYIEY YLVLDNGEFK RYNENQDEIR KRVFEMANYV NMLYKKLNTH VALVGMEIWT DKDKIKITPN ASFTLENFSK WRGSVLSRRK RHDIAQLITA TELAGTTVGL AFMSTMCSPY SVGVVQDHSD NLLRVAGTMA HEMGHNFGMF HDDYSCKCPS TICVMDKALS FYIPTDFSSC SRLSYDKFFE DKLSNCLFNA PLPTDIISTP ICGNQLVEMG EDCDCGTSEE CTNICCDAKT CK; Positive Samples: Raji, HT-29, A-549, THP-1, Mouse liver, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metallopeptidase domain 28; a disintegrin and metalloprotease domain 28; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 28; ADAM; ADAM 28; ADAMs; disintegrin 1; Disintegrin and metalloproteinase domain-containing protein 28; eMDC II; Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; MDC-L; metalloendopeptidases; metalloproteinase-disintegrin domain containing protein TECADAM; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L; TECADAM; Thymic epithelial cell-ADAM
Gene Aliases: ADAM 28; ADAM23; ADAM28; C130072N01Rik; D430033C21Rik; Dtgn1; eMDC II; eMDCII; MDC-L; MDC-Lm; MDC-Ls; MDCL; TECADAM
UniProt ID: (Human) Q9UKQ2, (Mouse) Q9JLN6
Entrez Gene ID: (Human) 10863, (Mouse) 13522, (Rat) 290344
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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