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OriGene
ADAMTS1 Monoclonal Antibody (OTI4F3), TrueMAB™
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FIGURE: 1 / 1
ADAMTS1 Antibody (TA804583) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ADAMTS1 (RC205984, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ADAM. Positive lysates LY416271 (100 µg) and LC416271 (20 µg) can be purchased separately from OriGene.
Product Details
TA804583
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4F3
Immunogen
Human recombinant protein fragment corresponding to amino acids 412-644 of human ADAMTS1 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ADAM-TS 1; ADAM-TS1; ADAMs; ADAMTS-1; human metalloproteinase with thrombospondin type 1 motifs; metalloendopeptidases; METH-1
Gene Aliases: ADAMTS1; C3-C5; KIAA1346; METH1
UniProt ID: (Human) Q9UHI8
Entrez Gene ID: (Human) 9510
ovulation from ovarian follicle
kidney development
proteolysis
integrin-mediated signaling pathway
negative regulation of cell proliferation
positive regulation of neuron projection development
tooth eruption
heart trabecula formation
cellular response to vitamin D
cellular response to parathyroid hormone stimulus
cellular response to prostaglandin E stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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