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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ADAMTS12 Antibodies

          Proteintech

          ADAMTS12 Polyclonal Antibody

          7 References
          View all (6) ADAMTS12 antibodies

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          Datasheet
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          Cite ADAMTS12 Polyclonal Antibody

          • Antibody Testing Data (7)
          ADAMTS12 Antibody in Immunocytochemistry (ICC/IF)
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          ADAMTS12 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          ADAMTS12 Antibody (24934-1-AP) in ICC/IF

          Immunofluorescent analysis of NIH/3T3 cells using 24934-1-AP (ADAMTS12 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ADAMTS12 Antibody in Immunocytochemistry (ICC/IF)
          ADAMTS12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAMTS12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAMTS12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAMTS12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAMTS12 Antibody in Western Blot (WB)
          ADAMTS12 Antibody in Western Blot (WB)

          Product Details

          24934-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200-1:1,000
          View 6 publications 6 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:20-1:200
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          ADAMTS12 Fusion Protein Ag20712 (1-229 aa encoded by BC058841)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.53 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MPCAQRSWL ANLSVVAQLL NFGALCYGRQ PQPGPVRFPD RRQEHFIKGL PEYHVVGPVR VDASGHFLSY GLHYPITSSR RKRDLDGSED WVYYRISHEE KDLFFNLTVN QGFLSNSYIM EKRYGNLSHV KMMASSAPLC HLSGTVLQQG TRVGTAALSA CHGLTGFFQL PHGDFFIEPV KKHPLVEGGY HPHIVYRRQK VPETKEPTCG LKGIVTHMSS WVEESVLFFW (1-229 aa encoded by BC058841)

          Target Information

          This protein is a disintegrin and metalloproteinase with thrombospondin motifs-12 (ADAMTS12), which is a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12; a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 12; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 12; ADAM-TS 12; ADAM-TS12; ADAMs; ADAMTS-12; metalloendopeptidases; metalloprotease disintegrin 12; UNQ1918

          View more View less

          Gene Aliases: ADAMTS-12; ADAMTS12; AI605170; PRO4389; UNQ1918/PRO4389

          View more View less

          UniProt ID: (Human) P58397, (Mouse) Q811B3

          View more View less

          Entrez Gene ID: (Human) 81792, (Mouse) 239337

          View more View less

          Function(s)
          metalloendopeptidase activity protein binding zinc ion binding peptidase activity metallopeptidase activity hydrolase activity metal ion binding
          Process(es)
          proteolysis cell-matrix adhesion cell migration proteoglycan catabolic process negative regulation of chondrocyte differentiation regulation of inflammatory response proteolysis involved in cellular protein catabolic process cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to BMP stimulus regulation of endothelial tube morphogenesis negative regulation of hepatocyte growth factor receptor signaling pathway negative regulation of cellular response to vascular endothelial growth factor stimulus negative regulation of cellular response to hepatocyte growth factor stimulus
          It has to be done as per old AB suggested Products section.
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