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In direct ELISAs, less than 1% cross-reactivity with recombinant human ADAMTS1, L1.2, L2, 3, 4, 5, 8, 10, 12, 13, and 16 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The immunizing peptide sequence is 100% conserved between human, mouse and rat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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