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          • Primary Antibodies ›
          • ADAMTS8 Antibodies

          Invitrogen

          ADAMTS8 Polyclonal Antibody

          View all (9) ADAMTS8 antibodies

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          Cite ADAMTS8 Polyclonal Antibody

          • Antibody Testing Data (2)
          ADAMTS8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          ADAMTS8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          ADAMTS8 Antibody (PA5-51350) in IHC (P)

          Immunohistochemical analysis of ADAMTS8 in paraffin embedded Human Liver cancer tissue using ADAMTS8 Polyclonal Antibody (Product # PA5-51350) at a 1:100 dilution. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ADAMTS8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ADAMTS8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-51350

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide of human ADAMTS8

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.6 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 40% glycerol

          Contains

          0.05% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2636797

          Product Specific Information

          The antibody detects endogenous levels of total ADAMTS8 protein.

          Peptide sequence: THKYAPFIII GLHLALGIFS FTLDTWSTSR GDTAEILGSG AGIACGSHVT

          Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

          The antibody detects endogenous levels of total ADAMTS8 protein.

          Target Information

          This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 8; ADAM-TS 8; ADAMs; ADAMTS-8; EC 3.4.24.14; EC 3.4.24.82; FLJ41712; metalloendopeptidases; METH-2; METH-8; METH2ADAM-TS METH-8

          View more View less

          Gene Aliases: ADAM-TS8; ADAMTS8; METH2

          View more View less

          UniProt ID: (Human) Q9UP79

          View more View less

          Entrez Gene ID: (Human) 11095

          View more View less

          Function(s)
          metalloendopeptidase activity integrin binding heparin binding metallopeptidase activity zinc ion binding low-affinity phosphate transmembrane transporter activity
          Process(es)
          proteolysis negative regulation of cell proliferation phosphate ion transmembrane transport
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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