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Abnova
ADCY2 Monoclonal Antibody (1D4)
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Product Details
H00000108-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
1D4
Immunogen
ADCY2 (NP_065433, 977 a.a. approximately 1086 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: GKLDAINKHS FNDFKLRVGI NHGPVIAGVI GAQKPQYDIW GNTVNVASRM DSTGVLDKIQ VTEETSLVLQ TLGYTCTCRG IINVKGKGDL KTYFVNTEMS RSLSQSNVAS
Target Information
ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3',5'-cyclic AMP synthetase; adenylate cyclase 2 (brain); adenylate cyclase II; Adenylate cyclase type 2; Adenylate cyclase type II; Adenylyl cyclase 2; ATP pyrophosphate-lyase 2; type II adenylate cyclase
Gene Aliases: AC2; ADCY2; HBAC2; KIAA1060
UniProt ID: (Human) Q08462
Entrez Gene ID: (Human) 108
renal water homeostasis
cAMP biosynthetic process
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
cAMP-mediated signaling
activation of protein kinase A activity
cellular response to glucagon stimulus
cellular response to forskolin
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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