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Immunogen sequence: MSTAGKVIK CKAAVLWELK KPFSIEEVEV APPKAHEVRI KMVAAGICRS DEHVVSGNLV TPLPVILGHE AAGIVESVGE GVTTVKPGDK VIPLFTPQCG KCRICKNPES NYCLKNDLGN PRGTLQDGTR RFTCSGKPIH HFVGVSTFSQ YTVVDENAVA KIDAASPLEK VCLIGCGFST GYGSAVKVAK VTPGSTCAVF GLGGVGLSVV MGCKAAGAAR IIAVDINKDK FAKAKELGAT ECINPQDYKK PIQEVLKEMT DGGVDFSFEV IGQLDTMMAS LLCCHEACGT SVIVGVPPDS QNLSINPMLL LTGRTWKGAI FGGFKSKESV PKLVADFMAK KFSLDALITN VLPFEKINEG FDLLRSGKSI RTVLT (1-374 aa encoded by BC062476)
This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADH, gamma subunit; Alcohol dehydrogenase 1C; alcohol dehydrogenase 3 (class I), gamma polypeptide; Alcohol dehydrogenase subunit gamma; aldehyde reductase
Gene Aliases: ADH1C; ADH3
UniProt ID: (Human) P00326
Entrez Gene ID: (Human) 126
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