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Recommended positive controls: HepG2, mouse lung, rat lung.
Predicted reactivity: Mouse (88%), Rat (87%), Pig (88%), Rabbit (88%), Chicken (83%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. A pseudogene that is located on chromosome 20 has been defined for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; aci-reductone dioxygenase; aci-reductone dioxygenase (ARD)-like protein 1; Acireductone dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Acireductone dioxygenase (Ni(2+)-requiring); Androgen-responsive ARD-like protein 1; androgen-responsive gene encoding an ARD-like protein; ARD; ARD {ECO:0000255|HAMAP-Rule:MF_03154}; ARD'; fe-ARD; fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; MT1-MMP cytoplasmic tail-binding protein-1; MTCBP-1; MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}; Sip-L; submergence induced protein 2; Submergence-induced protein-like factor
Gene Aliases: ADI1; AL024210; Alp1; APL1; ARD; Fe-ARD; HMFT1638; MTCBP-1; MTCBP1; mtnD; Ni-ARD; SIPL
UniProt ID: (Human) Q9BV57, (Rat) Q562C9, (Mouse) Q99JT9
Entrez Gene ID: (Human) 55256, (Rat) 298934, (Mouse) 104923
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