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Invitrogen
AEBP1 Polyclonal Antibody
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Product Details
PA5-109366
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 999-1158 of human AEBP1 (NP_001120.3).
Conjugate
Form
Liquid
Concentration
1.95 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854777
Product Specific Information
Immunogen sequence: NRPIPHIDPS RPMTPQQRRL QQRRLQHRLR LRAQMRLRRL NATTTLGPHT VPPTLPPAPA TTLSTTIEPW GLIPPTTAGW EESETETYTE VVTEFGTEVE PEFGTKVEPE FETQLEPEFE TQLEPEFEEE EEEEKEEEIA TGQAFPFTTV ETYTVNFGDF
Target Information
The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adipocyte enhancer-binding protein 1; AE-binding protein 1; Aortic carboxypeptidase-like protein; FLJ33612
Gene Aliases: ACLP; AEBP1
UniProt ID: (Human) Q8IUX7, (Rat) A2RUV9, (Mouse) Q640N1
Entrez Gene ID: (Human) 165, (Rat) 305494, (Mouse) 11568
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
carboxypeptidase activity
metallocarboxypeptidase activity
serine-type carboxypeptidase activity
calmodulin binding
zinc ion binding
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
transcription, DNA-templated
peptide metabolic process
muscle organ development
protein processing
regulation of transcription, DNA-templated
proteolysis
negative regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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