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AFAP1 Polyclonal Antibody

AFAP1 Antibody in Immunocytochemistry (ICC/IF)

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AFAP1 Antibody (21093-1-AP) in ICC/IF

Immunofluorescent analysis of MCF-7 cells using 21093-1-AP (AFAP1 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

AFAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

21093-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

AFAP1 Fusion Protein Ag15346 (382-730 aa encoded by BC032777)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DLKTHIVSI PLRGCEVIPG LDCKHPLTFR LLRNGQEVAV LEASSSEDMG RWIGILLAET GSSTDPEALH YDYIDVEMSA SVIQTAKQTF CFMNRRVISA NPYLGGTSNG YAHPSGTALH YDDVPCINGS LKGKKPPVAS NGVTGKGKTL SSQPKKADPA AVVKRTGSNA AQYKYGKNRV EADAKRLQTK EEELLKRKEA LRNRLAQLRK ERKDLRAAIE VNAGRKPQAI LEEKLKQLEE ECRQKEAERV SLELELTEVK ESLKKALAGG VTLGLAIEPK SGTSSPQSPV FRHRTLENSP ISSCDTSDTE GPVPVNSAAV LKKSQAAPGS SPCRGHVLRK AKEWELKNGT (382-730 aa encoded by BC032777)

Target Information

The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

CSNK2B modulates IRF1 binding to functional DNA elements and promotes basal and agonist-induced antiviral signaling.

Nucleic acids research

Matsumoto M,Modliszewski JL,Shinozaki K,Maezawa R,Perez VM,Ishikawa Y,Suzuki R,McKnight KL,Masaki T,Hirai-Yuki A,Kohara M,Lemon SM,Selitsky SR,Yamane D

Mon May 22 00:00:00 UTC 2023

Spatial proximity of proteins surrounding zyxin under force-bearing conditions.

Molecular biology of the cell

Cheah JS,Jacobs KA,Lai TW,Caballelo R,Yee JL,Ueda S,Heinrich V,Yamada S

Tue Jun 15 00:00:00 UTC 2021

Spatial proximity of proteins surrounding zyxin under force-bearing conditions.

Molecular biology of the cell

Cheah JS,Jacobs KA,Lai TW,Caballelo R,Yee JL,Ueda S,Heinrich V,Yamada S

Tue Jun 15 00:00:00 UTC 2021

Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore.

International journal of molecular medicine

Zhao Y,Guo Y,Chen Y,Liu S,Wu N,Jia D

Fri May 01 00:00:00 UTC 2020

LncRNA AFAP1-AS1 promotes tumorigenesis and epithelial-mesenchymal transition of osteosarcoma through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway.

Journal of experimental & clinical cancer research : CR

Shi D,Wu F,Mu S,Hu B,Zhong B,Gao F,Qing X,Liu J,Zhang Z,Shao Z

Fri Aug 23 00:00:00 UTC 2019

LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells.

Oncotarget

Shi X,Zhang H,Wang M,Xu X,Zhao Y,He R,Zhang M,Zhou M,Li X,Peng F,Shi C,Shen M,Wang X,Guo X,Qin R

Tue Aug 29 00:00:00 UTC 2017

Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer.

Biological research

Han X,Wang L,Ning Y,Li S,Wang Z

Tue Aug 30 00:00:00 UTC 2016

Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer.

Biological research

Han X,Wang L,Ning Y,Li S,Wang Z

Tue Aug 30 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: 110 kDa actin filament-associated protein; Actin filament-associated protein 1; actin filament-associated protein, 110 kDa; AFAP-110; FLJ56849

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Gene Aliases: 2600003E23Rik; 9630044L16Rik; AFAP; AFAP-110; AFAP1; AFAP110; AI848729; Kiaa3018; mKIAA3018

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UniProt ID: (Human) Q8N556, (Mouse) Q80YS6, (Rat) Q8VH46

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Entrez Gene ID: (Human) 60312, (Mouse) 70292, (Rat) 140935

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Function(s)

actin binding SH3 domain binding SH2 domain binding protein binding

Process(es)

regulation of signal transduction regulation of cytoskeleton organization signal transduction cellular response to mechanical stimulus

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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AFAP1 Polyclonal Antibody

AFAP1 Antibody (21093-1-AP) in ICC/IF

Product Details

21093-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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