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Immunogen sequence: SSPLPLVVNT WPFKNATEAA WRALASGGSA LDAVESGCAM CEREQCDGSV
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.
Aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Aspartylglucosaminidase; aspartylglucosylamine deaspartylase; Glycosylasparaginase; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase
Gene Aliases: AGA; AGU; ASRG; GA
UniProt ID: (Human) P20933
Entrez Gene ID: (Human) 175
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