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FIGURE: 1 / 2
Sequence of this protein is as follows: IAIKKEKRPP QTLSRGWGDD ITWVQTYEEG LFYAQKSKKP LMVIHHLEDC QYSQALKKVF AQNEEIQEMA QNKFIMLNLM HETTDKNLSP DGQYVPRIMF VDPSLTVRAD IAGRYSNRLY TYEPRDLPLL IENMKKALRL IQSEL
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
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Protein Aliases: AG-3; Anterior gradient 3 homolog; anterior gradient homolog 3; Anterior gradient protein 3; anterior gradient protein 3 homolog; Breast cancer membrane protein 11; H PDIA18; Protein disulfide isomerase family A, member 18
Gene Aliases: AG-3; AG3; AGR3; BCMP11; hAG-3; HAG3; PDIA18; UNQ642/PRO1272
UniProt ID: (Human) Q8TD06
Entrez Gene ID: (Human) 155465
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