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Proteintech
AGXT Polyclonal Antibody
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Product Details
22394-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AGXT Fusion Protein Ag18062 (1-392 aa encoded by BC132819)
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASHKLLVT PPKALLKPLS IPNQLLLGPG PSNLPPRIMA AGGLQMIGSM SKDMYQIMDE IKEGIQYVFQ TRNPLTLVIS GSGHCALEAA LVNVLEPGDS FLVGANGIWG QRAVDIGERI GARVHPMTKD PGGHYTLQEV EEGLAQHKPV LLFLTHGESS TGVLQPLDGF GELCHRYKCL LLVDSVASLG GTPLYMDRQG IDILYSGSQK ALNAPPGTSL ISFSDKAKKK MYSRKTKPFS FYLDIKWLAN FWGCDDQPRM YHHTIPVISL YSLRESLALI AEQGLENSWR QHREAAAYLH GRLQALGLQL FVKDPALRLP TVTTVAVPAG YDWRDIVSYV IDHFDIEIMG GLGPSTGKVL RIGLLGCNAT RENVDRVTEA LRAALQHCPK KKL (1-392 aa encoded by BC132819)
Target Information
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AGT; Alanine--glyoxylate aminotransferase; alanine-glyoxylate aminotransferase 1; hepatic peroxisomal alanine:glyoxylate aminotransferase; L-alanine: glyoxylate aminotransferase 1; Serine--pyruvate aminotransferase; Serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase, peroxisomal; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase; SPT
Gene Aliases: AGT; AGT1; AGXT; AGXT1; PH1; SPAT; SPT; TLH6
UniProt ID: (Human) P21549, (Mouse) O35423
Entrez Gene ID: (Human) 189, (Mouse) 11611
Notch signaling pathway
glyoxylate catabolic process
proteasomal protein catabolic process
glycine biosynthetic process, by transamination of glyoxylate
L-cysteine catabolic process
L-alanine catabolic process
pyruvate biosynthetic process
glyoxylate metabolic process
oxalic acid secretion
response to glucocorticoid
response to cAMP
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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